HDAC8 Antikörper (pSer39)

Produktnummer ABIN6255291

Produktdetails anti-HDAC8 Antikörper

Target: HDAC8 (Histone Deacetylase 8 (HDAC8))

Bindungsspezifität: pSer39

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HDAC8 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: Phospho-HDAC8 (Ser39) Antibody detects endogenous levels of HDAC8 only when phosphorylated at Serine 39.

Homologie: Pig,Zebrafish,Bovine,Sheep,Rabbit,Dog

Aufreinigung: The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.

Immunogen: A synthesized peptide derived from human HDAC8 around the phosphorylation site of Ser39.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu HDAC8

Target: HDAC8 (Histone Deacetylase 8 (HDAC8))

Andere Bezeichnung: HDAC8 (HDAC8 Produkte)

Synonyme: HD8 antikoerper, CDLS5 antikoerper, HDACL1 antikoerper, MRXS6 antikoerper, RPD3 antikoerper, WTS antikoerper, 2610007D20Rik antikoerper, RGD1562895 antikoerper, wu:fd19a02 antikoerper, zgc:66196 antikoerper, ATHDA8 antikoerper, HDA8 antikoerper, HISTONE DEACETYLASE 8 antikoerper, T27G7.14 antikoerper, T27G7_14 antikoerper, histone deacetylase 8 antikoerper, histone deacetylase 8 antikoerper, histone deacetylase 8 L homeolog antikoerper, CC1G_05302 antikoerper, hdac8 antikoerper, HDAC8 antikoerper, Hdac8 antikoerper, hdac8.L antikoerper, HDA08 antikoerper

Hintergrund:

Description: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Also involved in the deacetylation of cohesin complex protein SMC3 regulating release of cohesin complexes from chromatin. May play a role in smooth muscle cell contractility.

Gene: HDAC8

Molekulargewicht: 42kDa

Gen-ID: 55869

UniProt: Q9BY41

Pathways: Cellular Glucan Metabolic Process