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BCL2L1 Antikörper (pSer62)

Name: BCL2L1 Antikörper (pSer62)
SKU: ABIN6255430
Price: 698.46 EUR
Availability: InStock

BCL2L1 Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

Western blot analysis of Phospho-BCL-XL (Ser62) expression in various lysates (BCL2L1 Antikörper (pSer62))

Western blot analysis of BCL-XL phosphorylation expression in UV treated 293 whole cell lysates,The lane on the left is treated with the antigen-specific peptide. (BCL2L1 Antikörper (pSer62))

IF/ICC

ABIN6267624 at 1/100 staining human lung carcinoma tissue sections by IHC-P. (BCL2L1 Antikörper (pSer62))

IHC

4 Abbildungen

Produktnummer ABIN6255430

Datenblatt (PDF)

Target Alle BCL2L1 Antikörper anzeigen

BCL2L1 (BCL2-Like 1 (BCL2L1))
Bindungsspezifität
28

19

16

14

13

11

10

8

5

4

4

3

3

3

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
pSer62
Reaktivität
204

127

111

48

25

12

10

8

5

5

4

2

2

1
Human, Maus, Ratte
Wirt
152

69

2
Kaninchen
Passende Sekundärantikörper
Klonalität
143

80
Polyklonal
Konjugat
119

21

11

5

4

4

4

4

4

4

4

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1
Dieser BCL2L1 Antikörper ist unkonjugiert
Applikation
156

65

59

56

51

29

28

28

27

21

14

9

7

6

4

3

3

2

2

1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität

Phospho-BCL-XL (Ser62) Antibody detects endogenous levels of BCL-XL only when phosphorylated at Serine 62.

Homologie

Pig,Bovine,Horse,Sheep,Rabbit,Dog

Aufreinigung

The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.

Immunogen

A synthesized peptide derived from human BCL-XL around the phosphorylation site of Ser62.

Isotyp

IgG

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anti-BCL2-Like 1 (BCL2L1) (pSer62) antibody
BCL2L1 Reaktivität: Human WB, IHC, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

1 mg/mL

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

-20 °C

Informationen zur Lagerung

Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit

12 months
Target

BCL2L1 (BCL2-Like 1 (BCL2L1))

Andere Bezeichnung

BCL2L1 (BCL2L1 Produkte)

Synonyme

BCL-XL/S antikoerper, BCL2L antikoerper, BCLX antikoerper, BCLXL antikoerper, BCLXS antikoerper, Bcl-X antikoerper, PPP1R52 antikoerper, bcl-xL antikoerper, bcl-xS antikoerper, Bcl(X)L antikoerper, Bcl-XL antikoerper, Bcl-Xs antikoerper, Bcl2l antikoerper, BclX antikoerper, bcl-x antikoerper, Bcl-xl antikoerper, Bclx antikoerper, bcl-X antikoerper, Bcl-xL antikoerper, BCL-XL antikoerper, BCL2L1 antikoerper, bcl-XL antikoerper, bcl-x(l) antikoerper, bcl-xl/s antikoerper, bcl-xs antikoerper, bcl2l antikoerper, bclx antikoerper, bclxl antikoerper, xR11 antikoerper, bcl-xl antikoerper, blp1 antikoerper, cb1021 antikoerper, zfBLP1 antikoerper, BCL2 like 1 antikoerper, BCL2-like 1 antikoerper, Bcl2-like 1 antikoerper, BCL2-like 1 L homeolog antikoerper, bcl2-like 1 antikoerper, BCL2L1 antikoerper, Bcl2l1 antikoerper, bcl2l1 antikoerper, bcl2l1.L antikoerper

Hintergrund

Description: Potent inhibitor of cell death. Inhibits activation of caspases. Appears to regulate cell death by blocking the voltage-dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis.
Gene: BCL2L1

Molekulargewicht

30kDa

Gen-ID

598

UniProt

Q07817

Pathways

Apoptose, Negative Regulation of intrinsic apoptotic Signaling