Cyclin H Antikörper (pThr315)
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- Target Alle Cyclin H (CCNH) Antikörper anzeigen
- Cyclin H (CCNH)
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Bindungsspezifität
- pThr315
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Cyclin H Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Spezifität
- Phospho-Cyclin H (Thr315) Antibody detects endogenous levels of Cyclin H only when phosphorylated at Thr315.
- Homologie
- Pig,Zebrafish,Horse,Sheep,Rabbit,Dog,Chicken
- Aufreinigung
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
- Immunogen
- A synthesized peptide derived from human Cyclin H around the phosphorylation site of Thr315.
- Isotyp
- IgG
- Top Product
- Discover our top product CCNH Primärantikörper
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anti-Cyclin H (CCNH) (AA 1-110) antibody
CCNH Reaktivität: Human WB, ELISA, IF, IHC (p) Wirt: Maus Monoclonal 1B8 unconjugated
anti-Cyclin H (CCNH) (AA 1-323) antibodyCCNH Reaktivität: Human WB, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Cyclin H (CCNH) (AA 269-299), (C-Term) antibodyCCNH Reaktivität: Human WB, FACS Wirt: Kaninchen Polyclonal RB14888 unconjugated
anti-Cyclin H (CCNH) (AA 1-323) antibodyCCNH Reaktivität: Human WB, IF Wirt: Maus Polyclonal unconjugated
anti-Cyclin H (CCNH) (AA 261-319) antibodyCCNH Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Cyclin H (CCNH) (AA 221-323) antibodyCCNH Reaktivität: Human, Ratte WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Cyclin H (CCNH) (AA 24-52), (N-Term) antibodyCCNH Reaktivität: Maus WB, FACS Wirt: Kaninchen Polyclonal RB14999 unconjugated
anti-Cyclin H (CCNH) antibodyCCNH Reaktivität: Human WB, IP Wirt: Maus Monoclonal unconjugated
anti-Cyclin H (CCNH) (C-Term) antibodyCCNH Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Cyclin H (CCNH) (C-Term) antibodyCCNH Reaktivität: Human, Maus, Ratte, Schwein, Meerschweinchen, Kaninchen, Affe, Pferd, Rind (Kuh), Fledermaus WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- Cyclin H (CCNH)
- Andere Bezeichnung
- CCNH (CCNH Produkte)
- Hintergrund
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Description: Regulates CDK7, the catalytic subunit of the CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle.
Gene: CCNH
- Molekulargewicht
- 37.6 kDa
- Gen-ID
- 902
- UniProt
- P51946
- Pathways
- Zellzyklus, Mitotic G1-G1/S Phases, M Phase
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