ICAM1 Antikörper (pTyr512)
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- Target Alle ICAM1 Antikörper anzeigen
- ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))
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Bindungsspezifität
- pTyr512
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ICAM1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- Spezifität
- Phospho-ICAM-1 (Tyr512) Antibody detects endogenous levels of ICAM-1 only when phosphorylated at Tyrosine 512
- Kreuzreaktivität
- Human, Maus
- Aufreinigung
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
- Immunogen
- A synthesized peptide derived from human ICAM-1 around the phosphorylation site of Tyrosine 512
- Isotyp
- IgG
- Top Product
- Discover our top product ICAM1 Primärantikörper
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- Applikationshinweise
- WB 1:500-1:2000 IHC 1:50-1:200, IF/ICC 1:100-1:500
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C.Stable for 12 months from date of receipt
- Haltbarkeit
- 12 months
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- Target
- ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))
- Andere Bezeichnung
- ICAM-1 (ICAM1 Produkte)
- Synonyme
- BB2 antikoerper, CD54 antikoerper, P3.58 antikoerper, Icam-1 antikoerper, Ly-47 antikoerper, MALA-2 antikoerper, ICAM antikoerper, ICAM-1 antikoerper, ICAM1 antikoerper, intercellular adhesion molecule 1 antikoerper, intercellular adhesion molecule-1 antikoerper, ICAM1 antikoerper, Icam1 antikoerper, ICAM-1 antikoerper
- Substanzklasse
- Viral Protein
- Hintergrund
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Description: ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation.
Gene: ICAM1
- Molekulargewicht
- 92kDa
- Gen-ID
- 3383
- UniProt
- P05362
- Pathways
- Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Regulation of Leukocyte Mediated Immunity, Thromboxane A2 Receptor Signaling
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