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SHP1 Antikörper (pTyr536)

Name: SHP1 Antikörper (pTyr536)
SKU: ABIN6255949
Price: 698.46 EUR
Availability: InStock

PTPN6 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

Western blot analysis of SHP-1 phosphorylation expression in EGF treated RAW264. (SHP1 Antikörper (pTyr536))

ABIN6267455 staining RAW264. (SHP1 Antikörper (pTyr536))

IF/ICC

ABIN6267455 at 1/100 staining human bone tissue sections by IHC-P. (SHP1 Antikörper (pTyr536))

IHC

Western blot analysis of Phospho-SHP-1 (Tyr536) expression in various lysates (SHP1 Antikörper (pTyr536))

4 Abbildungen

Produktnummer ABIN6255949

Datenblatt (PDF)

Target Alle SHP1 (PTPN6) Antikörper anzeigen

SHP1 (PTPN6) (Protein-tyrosine Phosphatase 1C (PTPN6))
Bindungsspezifität
34

12

7

7

6

5

3

3

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
pTyr536
Reaktivität
117

72

54

4

3

2

2

2

1

1

1

1
Human, Maus, Ratte
Wirt
106

13

1
Kaninchen
Passende Sekundärantikörper
Klonalität
100

20
Polyklonal
Konjugat
55

7

5

4

4

4

4

4

4

3

2

2

2

2

2

2

2

2

2

2

2

2

1

1
Dieser SHP1 Antikörper ist unkonjugiert
Applikation
82

30

22

20

20

14

14

10

9

7

4

4

2

2

1

1

1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität

Phospho-SHP1 (Tyr536) Antibody detects endogenous levels of SHP1 only when phosphorylated at Tyrosine 536.

Homologie

Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken

Aufreinigung

The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.

Immunogen

A synthesized peptide derived from human SHP1 around the phosphorylation site of Tyr536.

Isotyp

IgG

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PTPN6 Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated

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anti-Protein-tyrosine Phosphatase 1C (PTPN6) (AA 100-400) antibody
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anti-Protein-tyrosine Phosphatase 1C (PTPN6) (AA 492-597) antibody
PTPN6 Reaktivität: Human, Maus, Ratte, Hund WB, IHC, IF, IP Wirt: Maus Monoclonal 52-PTP1C-SHP1 unconjugated

anti-Protein-tyrosine Phosphatase 1C (PTPN6) antibody
PTPN6 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

1 mg/mL

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

-20 °C

Informationen zur Lagerung

Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit

12 months
Target

SHP1 (PTPN6) (Protein-tyrosine Phosphatase 1C (PTPN6))

Andere Bezeichnung

PTPN6 (PTPN6 Produkte)

Synonyme

HCPH antikoerper, HPTP1C antikoerper, PTP-1C antikoerper, SH-PTP1 antikoerper, SHP-1 antikoerper, SHP-1L antikoerper, SHP1 antikoerper, DRPLA antikoerper, Hcph antikoerper, Ptp1C antikoerper, me antikoerper, motheaten antikoerper, Ptph6 antikoerper, Shp-1 antikoerper, fj22f05 antikoerper, wu:fj22f05 antikoerper, zgc:55501 antikoerper, ptpn6 antikoerper, protein tyrosine phosphatase, non-receptor type 6 antikoerper, protein tyrosine phosphatase, non-receptor type 6 L homeolog antikoerper, PTPN6 antikoerper, Ptpn6 antikoerper, ptpn6 antikoerper, ptpn6.L antikoerper

Hintergrund

Description: Modulates signaling by tyrosine phosphorylated cell surface receptors such as KIT and the EGF receptor/EGFR. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates. Together with MTUS1, induces UBE2V2 expression upon angiotensin II stimulation. Plays a key role in hematopoiesis.
Gene: PTPN6

Molekulargewicht

67kDa

Gen-ID

5777

UniProt

P29350

Pathways

JAK-STAT Signalweg, T-Zell Rezeptor Signalweg, TLR Signalweg, Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Response to Growth Hormone Stimulus, Regulation of Leukocyte Mediated Immunity, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, BCR Signaling