VASP Antikörper (pSer157)
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- Target Alle VASP Antikörper anzeigen
- VASP (Vasodilator-Stimulated phosphoprotein (VASP))
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Bindungsspezifität
- pSer157
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser VASP Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- Spezifität
- Phospho-VASP (Ser157) Antibody detects endogenous levels of VASP only when phosphorylated at Serine 157.
- Homologie
- Pig,Bovine,Sheep,Dog
- Aufreinigung
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
- Immunogen
- A synthesized peptide derived from human VASP around the phosphorylation site of Ser157.
- Isotyp
- IgG
- Top Product
- Discover our top product VASP Primärantikörper
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- Applikationshinweise
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- VASP (Vasodilator-Stimulated phosphoprotein (VASP))
- Andere Bezeichnung
- VASP (VASP Produkte)
- Hintergrund
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Description: Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. VASP promotes actin filament elongation. It protects the barbed end of growing actin filaments against capping and increases the rate of actin polymerization in the presence of capping protein. VASP stimulates actin filament elongation by promoting the transfer of profilin-bound actin monomers onto the barbed end of growing actin filaments. Plays a role in actin-based mobility of Listeria monocytogenes in host cells. Regulates actin dynamics in platelets and plays an important role in regulating platelet aggregation.
Gene: VASP
- Molekulargewicht
- 46kDa
- Gen-ID
- 7408
- UniProt
- P50552
- Pathways
- T-Zell Rezeptor Signalweg, Regulation of Actin Filament Polymerization, Tube Formation
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