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IRS1 Antikörper (pSer312)

IRS1 Reaktivität: Human, Maus, Ratte, Affe WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6256264
  • Target Alle IRS1 Antikörper anzeigen
    IRS1 (Insulin Receptor Substrate 1 (IRS1))
    Bindungsspezifität
    • 32
    • 28
    • 28
    • 27
    • 25
    • 21
    • 18
    • 17
    • 16
    • 16
    • 16
    • 7
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer312
    Reaktivität
    • 317
    • 255
    • 231
    • 24
    • 18
    • 18
    • 17
    • 16
    • 16
    • 15
    • 2
    • 1
    • 1
    Human, Maus, Ratte, Affe
    Wirt
    • 314
    • 16
    Kaninchen
    Klonalität
    • 308
    • 22
    Polyklonal
    Konjugat
    • 138
    • 14
    • 11
    • 10
    • 10
    • 10
    • 10
    • 10
    • 10
    • 10
    • 10
    • 10
    • 10
    • 10
    • 10
    • 10
    • 7
    • 6
    • 6
    • 6
    • 6
    • 6
    Dieser IRS1 Antikörper ist unkonjugiert
    Applikation
    • 171
    • 126
    • 104
    • 92
    • 91
    • 65
    • 61
    • 49
    • 24
    • 18
    • 11
    • 7
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Spezifität
    Phospho-IRS-1 (Ser312) Antibody detects endogenous levels of IRS-1 only when phosphorylated at Serine 312
    Kreuzreaktivität
    Human, Affe, Maus, Ratte (Rattus)
    Aufreinigung
    The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
    Immunogen
    A synthesized peptide derived from human IRS-1 around the phosphorylation site of Serine 312
    Isotyp
    IgG
    Top Product
    Discover our top product IRS1 Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000 IF/ICC 1:100-1:500 IHC 1:50-1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C.Stable for 12 months from date of receipt
    Haltbarkeit
    12 months
  • Target
    IRS1 (Insulin Receptor Substrate 1 (IRS1))
    Andere Bezeichnung
    IRS-1 (IRS1 Produkte)
    Synonyme
    HIRS-1 antikoerper, G972R antikoerper, IRS-1 antikoerper, IRS1IRM antikoerper, irs1 antikoerper, irsu antikoerper, IRS1 antikoerper, irs-1 antikoerper, irs1-a antikoerper, insulin receptor substrate 1 antikoerper, insulin receptor substrate 2 antikoerper, insulin receptor substrate 1 S homeolog antikoerper, IRS1 antikoerper, Irs1 antikoerper, irs2 antikoerper, irs1.S antikoerper
    Hintergrund

    Description: May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit (By similarity).

    Gene: IRS1

    Molekulargewicht
    180kDa
    Gen-ID
    3667
    UniProt
    P35568
    Pathways
    Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Negative Regulation of Hormone Secretion, Response to Growth Hormone Stimulus, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process
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