CXCR2 Antikörper (pSer347)

Produktnummer ABIN6256283

Produktdetails anti-CXCR2 Antikörper

Target: CXCR2 (Chemokine (C-X-C Motif) Receptor 2 (CXCR2))

Bindungsspezifität: pSer347

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CXCR2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: Phospho-IL-8R beta/CDw128 beta (Ser347) Antibody detects endogenous levels of IL-8R beta/CDw128 beta only when phosphorylated at Serine 347

Kreuzreaktivität: Human, Maus

Aufreinigung: The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.

Immunogen: A synthesized peptide derived from human IL-8R beta/CDw128 beta around the phosphorylation site of Serine 347

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000 IHC 1:50-1:200 IF/ICC 1:100-1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C.Stable for 12 months from date of receipt

Haltbarkeit: 12 months

Details zu CXCR2

Target: CXCR2 (Chemokine (C-X-C Motif) Receptor 2 (CXCR2))

Andere Bezeichnung: IL-8R beta/CDw128 beta (CXCR2 Produkte)

Synonyme: CD182 antikoerper, CDw128b antikoerper, CMKAR2 antikoerper, IL8R2 antikoerper, IL8RA antikoerper, IL8RB antikoerper, CXC-R2 antikoerper, CXCR-2 antikoerper, CD128 antikoerper, CDw128 antikoerper, Cmkar2 antikoerper, Gpcr16 antikoerper, IL-8Rh antikoerper, IL-8rb antikoerper, Il8rb antikoerper, mIL-8RH antikoerper, C-X-C motif chemokine receptor 2 antikoerper, chemokine (C-X-C motif) receptor 2 antikoerper, Cxcr2 antikoerper, CXCR2 antikoerper

Hintergrund:

Description: Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2.

Gene: CXCR2

Molekulargewicht: 48kDa

Gen-ID: 3579

UniProt: P25025

Pathways: cAMP Metabolic Process