Aryl Hydrocarbon Receptor Antikörper (pSer36)
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- Target Alle Aryl Hydrocarbon Receptor (AHR) Antikörper anzeigen
- Aryl Hydrocarbon Receptor (AHR)
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Bindungsspezifität
- pSer36
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Aryl Hydrocarbon Receptor Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- Spezifität
- Phospho-AhR (Ser36) Antibody detects endogenous levels of AhR only when phosphorylated at Serine 36
- Kreuzreaktivität
- Human, Maus, Ratte (Rattus)
- Aufreinigung
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
- Immunogen
- A synthesized peptide derived from human AhR around the phosphorylation site of Serine 36
- Isotyp
- IgG
- Top Product
- Discover our top product AHR Primärantikörper
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- Applikationshinweise
- WB 1:500-1:2000 IHC 1:50-1:200, IF/ICC 1:100-1:500
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C.Stable for 12 months from date of receipt
- Haltbarkeit
- 12 months
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- Target
- Aryl Hydrocarbon Receptor (AHR)
- Andere Bezeichnung
- AhR (AHR Produkte)
- Synonyme
- AHR antikoerper, ahr1 antikoerper, ahr antikoerper, bHLHe76 antikoerper, Ah antikoerper, Ahh antikoerper, Ahre antikoerper, In antikoerper, aryl hydrocarbon receptor S homeolog antikoerper, aryl hydrocarbon receptor antikoerper, aryl-hydrocarbon receptor antikoerper, ahr.S antikoerper, AHR antikoerper, ahr antikoerper, Ahr antikoerper
- Hintergrund
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Description: Ligand-activated transcriptional activator. Binds to the XRE promoter region of genes it activates. Activates the expression of multiple phase I and II xenobiotic chemical metabolizing enzyme genes (such as the CYP1A1 gene). Mediates biochemical and toxic effects of halogenated aromatic hydrocarbons. Involved in cell-cycle regulation. Likely to play an important role in the development and maturation of many tissues. Regulates the circadian clock by inhibiting the basal and circadian expression of the core circadian component PER1. Inhibits PER1 by repressing the CLOCK-ARNTL/BMAL1 heterodimer mediated transcriptional activation of PER1.
Gene: AHR
- Molekulargewicht
- 90kDa
- Gen-ID
- 196
- UniProt
- P35869, A9YTQ3
- Pathways
- Regulation of Cell Size
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