PDCD4 Antikörper (pSer457)

Produktnummer ABIN6256345

Produktdetails anti-PDCD4 Antikörper

Target: PDCD4 (Programmed Cell Death 4 (PDCD4))

Bindungsspezifität: pSer457

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDCD4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: Phospho-PDCD4 (Ser457) Antibody detects endogenous levels of PDCD4 only when phosphorylated at Serine 457.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Aufreinigung: The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.

Immunogen: A synthesized peptide derived from human PDCD4 around the phosphorylation site of Ser457.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu PDCD4

Target: PDCD4 (Programmed Cell Death 4 (PDCD4))

Andere Bezeichnung: PDCD4 (PDCD4 Produkte)

Synonyme: H731 antikoerper, D19Ucla1 antikoerper, Ma3 antikoerper, Tis antikoerper, Dug antikoerper, cb45 antikoerper, pdcd4 antikoerper, sb:cb45 antikoerper, wu:fc84b08 antikoerper, h731 antikoerper, MGC69337 antikoerper, PDCD4 antikoerper, wu:fa55g03 antikoerper, wu:fb08a11 antikoerper, wu:fe01a02 antikoerper, zgc:66311 antikoerper, programmed cell death 4 antikoerper, programmed cell death 4b antikoerper, programmed cell death 4 L homeolog antikoerper, programmed cell death 4 (neoplastic transformation inhibitor) antikoerper, programmed cell death 4a antikoerper, PDCD4 antikoerper, Pdcd4 antikoerper, pdcd4b antikoerper, pdcd4.L antikoerper, pdcd4 antikoerper, pdcd4a antikoerper

Hintergrund:

Description: Inhibits translation initiation and cap-dependent translation. May excert its function by hindering the interaction between EIF4A1 and EIF4G. Inhibits the helicase activity of EIF4A. Modulates the activation of JUN kinase. Down-regulates the expression of MAP4K1, thus inhibiting events important in driving invasion, namely, MAPK85 activation and consequent JUN-dependent transcription. May play a role in apoptosis. Tumor suppressor. Inhibits tumor promoter-induced neoplastic transformation. Binds RNA (By similarity).

Gene: PDCD4

Molekulargewicht: 51kDa

Gen-ID: 27250

UniProt: Q53EL6