HDAC4 Antikörper (pSer632)
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- Target Alle HDAC4 Antikörper anzeigen
- HDAC4 (Histone Deacetylase 4 (HDAC4))
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Bindungsspezifität
- pSer632
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser HDAC4 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- Spezifität
- Phospho-HDAC4 (Ser632) Antibody detects endogenous levels of HDAC4 only when phosphorylated at Serine 632.
- Homologie
- Pig,Zebrafish,Bovine,Sheep,Dog,Chicken,Xenopus
- Aufreinigung
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
- Immunogen
- A synthesized peptide derived from human HDAC4 around the phosphorylation site of Ser632.
- Isotyp
- IgG
- Top Product
- Discover our top product HDAC4 Primärantikörper
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anti-Histone Deacetylase 4 (HDAC4) (AA 904-1076) antibody
HDAC4 Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
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anti-Histone Deacetylase 4 (HDAC4) (AA 451-650) antibodyHDAC4 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Histone Deacetylase 4 (HDAC4) (AA 1049-1077) antibodyHDAC4 Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Histone Deacetylase 4 (HDAC4) (AA 1049-1077), (C-Term) antibodyHDAC4 Reaktivität: Human WB, IF, IHC (p) Wirt: Kaninchen Polyclonal RB33667 unconjugated
anti-Histone Deacetylase 4 (HDAC4) (AA 530-630) antibodyHDAC4 Reaktivität: Human WB, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Histone Deacetylase 4 (HDAC4) (Ser632) antibodyHDAC4 Reaktivität: Human WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- HDAC4 (Histone Deacetylase 4 (HDAC4))
- Andere Bezeichnung
- HDAC4 (HDAC4 Produkte)
- Hintergrund
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Description: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer. Deacetylates HSPA1A and HSPA1B at 'Lys-77' leading to their preferential binding to co-chaperone STUB1 (PubMed:27708256).
Gene: HDAC4
- Molekulargewicht
- 119kDa
- Gen-ID
- 9759
- UniProt
- P56524
- Pathways
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process
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