Histone H2A Antikörper (pThr121)
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- Target Alle Histone H2A Antikörper anzeigen
- Histone H2A
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Bindungsspezifität
- pThr121
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Reaktivität
- Human, Ratte, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Histone H2A Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- Spezifität
- Phospho-Histone H2A (Thr121) Antibody detects endogenous levels of Histone H2A only when phosphorylated at Threonine 121
- Kreuzreaktivität
- Human, Maus, Ratte (Rattus)
- Aufreinigung
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
- Immunogen
- A synthesized peptide derived from human Histone H2A around the phosphorylation site of Threonine 121
- Isotyp
- IgG
- Top Product
- Discover our top product Histone H2A Primärantikörper
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- Applikationshinweise
- IHC 1:50-1:200 WB 1:1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C.Stable for 12 months from date of receipt
- Haltbarkeit
- 12 months
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- Target
- Histone H2A
- Abstract
- Histone H2A Produkte
- Hintergrund
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Description: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Gene: HIST1H2AG, HIST1H2AI, HIST1H2AK, HIST1H2AL, HIST1H2AM
- Molekulargewicht
- 15kDa
- Gen-ID
- 83, 298, 330
- UniProt
- P0C0S8, P04908, P20671, Q96KK5, Q6FI13, Q7L7L0
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