BRAF Antikörper (pThr599)

Produktnummer ABIN6256588

Produktdetails anti-BRAF Antikörper

Target: BRAF (B-Raf proto-oncogene, serine/threonine kinase (BRAF))

Bindungsspezifität: pThr599

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BRAF Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: Phospho-B Raf (Thr599) Antibody detects endogenous levels of B Raf only when phosphorylated at Threonine 599.

Homologie: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Aufreinigung: The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.

Immunogen: A synthesized peptide derived from human B Raf around the phosphorylation site of Thr599.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:50-1:200, WB 1:500-2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu BRAF

Target: BRAF (B-Raf proto-oncogene, serine/threonine kinase (BRAF))

Andere Bezeichnung: BRAF (BRAF Produkte)

Synonyme: B-RAF1 antikoerper, BRAF1 antikoerper, NS7 antikoerper, RAFB1 antikoerper, C-RMIL antikoerper, RMIL antikoerper, B-Raf antikoerper, braf1 antikoerper, rafb1 antikoerper, b-raf1 antikoerper, sierrabraf antikoerper, BRAF antikoerper, 9930012E13Rik antikoerper, AA120551 antikoerper, AA387315 antikoerper, AA473386 antikoerper, B-raf antikoerper, Braf-2 antikoerper, Braf2 antikoerper, C230098H17 antikoerper, C87398 antikoerper, D6Ertd631e antikoerper, braf antikoerper, fc48g01 antikoerper, wu:fc48g01 antikoerper, B-Raf proto-oncogene, serine/threonine kinase antikoerper, B-Raf proto-oncogene, serine/threonine kinase S homeolog antikoerper, Braf transforming gene antikoerper, si:dkey-222f8.3 antikoerper, BRAF antikoerper, Braf antikoerper, braf.S antikoerper, braf antikoerper, si:dkey-222f8.3 antikoerper

Hintergrund:

Description: Protein kinase involved in the transduction of mitogenic signals from the cell membrane to the nucleus. May play a role in the postsynaptic responses of hippocampal neuron. Phosphorylates MAP2K1, and thereby contributes to the MAP kinase signal transduction pathway.

Gene: BRAF

Molekulargewicht: 85kDa

Gen-ID: 673

UniProt: P15056

Pathways: MAPK Signalweg, RTK Signalweg, Neurotrophin Signalübertragung, Ribonucleoprotein Complex Subunit Organization, Hepatitis C, Autophagie