Crk Antikörper (pTyr221)

Produktnummer ABIN6256674

Produktdetails anti-Crk Antikörper

Target: Crk (CRK) (V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian) (CRK))

Bindungsspezifität: pTyr221

Reaktivität: Human, Maus, Ratte, Affe

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Crk Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: Phospho-CrkII (Tyr221) Antibody detects endogenous levels of CrkII only when phosphorylated at Tyrosine 221

Kreuzreaktivität: Human, Affe, Maus, Ratte (Rattus)

Aufreinigung: The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.

Immunogen: A synthesized peptide derived from human CrkII around the phosphorylation site of Tyrosine 221

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000 IF/ICC 1:100-1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C.Stable for 12 months from date of receipt

Haltbarkeit: 12 months

Details zu Crk

Target: Crk (CRK) (V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian) (CRK))

Andere Bezeichnung: CrkII (CRK Produkte)

Synonyme: CG1587 antikoerper, CRK antikoerper, D-CRK antikoerper, D-Crk antikoerper, DCrk antikoerper, Dcrk antikoerper, Dmel\\CG1587 antikoerper, crk antikoerper, dCRK antikoerper, dCrk antikoerper, fb34h10 antikoerper, fc05a01 antikoerper, fi19g05 antikoerper, wu:fb34h10 antikoerper, wu:fc05a01 antikoerper, wu:fc54a04 antikoerper, wu:fi19g05 antikoerper, zgc:100936 antikoerper, CRKII antikoerper, p38 antikoerper, Crko antikoerper, crk2 antikoerper, crkII antikoerper, v-crk antikoerper, P38C-CRK antikoerper, Crk-I antikoerper, Crk-II antikoerper, Crk-III antikoerper, Crk3 antikoerper, CrkIII antikoerper, c-Crk antikoerper, Crk oncogene antikoerper, v-crk avian sarcoma virus CT10 oncogene homolog antikoerper, CRK proto-oncogene, adaptor protein antikoerper, v-crk avian sarcoma virus CT10 oncogene homolog L homeolog antikoerper, v-crk sarcoma virus CT10 oncogene homolog antikoerper, Crk antikoerper, crk antikoerper, CRK antikoerper, crk.L antikoerper

Hintergrund:

Description: Isoform Crk-II: Regulates cell adhesion, spreading and migration. Mediates attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. Involved in phagocytosis of apoptotic cells and cell motility via its interaction with DOCK1 and DOCK4. May regulate the EFNA5-EPHA3 signaling.

Gene: CRK

Molekulargewicht: 42kDa

Gen-ID: 1398

UniProt: P46108

Pathways: Neurotrophin Signalübertragung, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor