Tumor Protein p73 Antikörper (pTyr99)
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- Target Alle Tumor Protein p73 (TP73) Antikörper anzeigen
- Tumor Protein p73 (TP73) (Tumor Protein P73 (TP73))
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Bindungsspezifität
- pTyr99
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Tumor Protein p73 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Spezifität
- Phospho-p73 (Tyr99) Antibody detects endogenous levels of p73 only when phosphorylated at Tyrosine 99.
- Homologie
- Pig,Bovine,Sheep,Dog,Chicken
- Aufreinigung
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
- Immunogen
- A synthesized peptide derived from human p73 around the phosphorylation site of Tyr99.
- Isotyp
- IgG
- Top Product
- Discover our top product TP73 Primärantikörper
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- Applikationshinweise
- WB 1:500-1:2000, IHC 1:50-1:1000, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- Tumor Protein p73 (TP73) (Tumor Protein P73 (TP73))
- Andere Bezeichnung
- TP73 (TP73 Produkte)
- Hintergrund
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Description: Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.
Gene: TP73
- Molekulargewicht
- 80kDa
- Gen-ID
- 7161
- UniProt
- O15350
- Pathways
- Regulation of Cell Size, Positive Regulation of Response to DNA Damage Stimulus
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