KDM5D Antikörper (C-Term)

Produktnummer ABIN6256832

Produktdetails anti-KDM5D Antikörper

Target: KDM5D (Lysine (K)-Specific Demethylase 5D (KDM5D))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KDM5D Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Spezifität: JAD1D Antibody detects endogenous levels of total JAD1D.

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human JAD1D, corresponding to a region within C-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu KDM5D

Target: KDM5D (Lysine (K)-Specific Demethylase 5D (KDM5D))

Andere Bezeichnung: KDM5D (KDM5D Produkte)

Synonyme: JARID1D antikoerper, Jarid1d antikoerper, DKFZp468I1010 antikoerper, HY antikoerper, HYA antikoerper, SMCY antikoerper, Smcy antikoerper, lysine demethylase 5D antikoerper, lysine (K)-specific demethylase 5D antikoerper, lysine demethylase 5C antikoerper, KDM5D antikoerper, Kdm5d antikoerper, KDM5C antikoerper

Hintergrund:

Description: Histone demethylase that specifically demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'. May play a role in spermatogenesis. Involved in transcriptional repression of diverse metastasis-associated genes, in this function seems to cooperate with ZMYND8. Suppresses prostate cancer cell invasion. Regulates androgen receptor (AR) transcriptional activity by demethylating H3K4me3 active transcription marks.

Gene: KDM5D

Gen-ID: 8284

UniProt: Q9BY66

Pathways: Warburg Effekt