Serotonin Receptor 6 Antikörper (Internal Region)

Produktnummer ABIN6256884

Produktdetails anti-Serotonin Receptor 6 Antikörper

Target: Serotonin Receptor 6 (HTR6)

Bindungsspezifität: Internal Region

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Serotonin Receptor 6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Spezifität: 5HT6 Receptor Antibody detects endogenous levels of total 5HT6 Receptor.

Homologie: Pig,Bovine,Horse,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human 5HT6 Receptor, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu Serotonin Receptor 6

Target: Serotonin Receptor 6 (HTR6)

Andere Bezeichnung: HTR6 (HTR6 Produkte)

Synonyme: 5-HT6 antikoerper, 5-HT6R antikoerper, 5-hydroxytryptamine (serotonin) receptor 6 antikoerper, 5-hydroxytryptamine receptor 6 antikoerper, Htr6 antikoerper, HTR6 antikoerper

Hintergrund:

Description: This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase. It has a high affinity for tricyclic psychotropic drugs (By similarity). Controls pyramidal neurons migration during corticogenesis, through the regulation of CDK5 activity (By similarity). Is an activator of TOR signaling (PubMed:23027611).

Gene: HTR6

Molekulargewicht: 47 kDa

Gen-ID: 3362

UniProt: P50406

Pathways: JAK-STAT Signalweg