AIM2 Antikörper (Internal Region)
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- Target Alle AIM2 Antikörper anzeigen
- AIM2 (Absent in Melanoma 2 (AIM2))
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Bindungsspezifität
- Internal Region
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser AIM2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- Spezifität
- AIM2 Antibody detects endogenous levels of total AIM2.
- Homologie
- Horse
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human AIM2, corresponding to a region within the internal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product AIM2 Primärantikörper
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anti-Absent in Melanoma 2 (AIM2) (AA 1-195) antibody
AIM2 Reaktivität: Human ELISA, FACS, ICC Wirt: Maus Monoclonal 3C4G11 unconjugated
anti-Absent in Melanoma 2 (AIM2) (AA 1-343) antibodyAIM2 Reaktivität: Human WB, IHC, ICC, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Absent in Melanoma 2 (AIM2) (AA 1-50) antibodyAIM2 Reaktivität: Human WB, ELISA, IF, FACS Wirt: Kaninchen Polyclonal unconjugated
anti-Absent in Melanoma 2 (AIM2) (AA 81-326) antibodyAIM2 Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Absent in Melanoma 2 (AIM2) (AA 4-32), (N-Term) antibodyAIM2 Reaktivität: Human WB, IF, FACS Wirt: Kaninchen Polyclonal RB23659 unconjugated
anti-Absent in Melanoma 2 (AIM2) (AA 1-343) antibodyAIM2 Reaktivität: Human WB, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Absent in Melanoma 2 (AIM2) (AA 1-343) antibodyAIM2 Reaktivität: Human WB, IF Wirt: Maus Polyclonal unconjugated
anti-Absent in Melanoma 2 (AIM2) (AA 1-260) antibodyAIM2 Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Absent in Melanoma 2 (AIM2) (AA 14-215) antibodyAIM2 Reaktivität: Human, Maus, Ratte WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Absent in Melanoma 2 (AIM2) (AA 255-354) antibodyAIM2 Reaktivität: Human, Maus, Ratte WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- AIM2 (Absent in Melanoma 2 (AIM2))
- Andere Bezeichnung
- AIM2 (AIM2 Produkte)
- Synonyme
- AIM2 antikoerper, PYHIN4 antikoerper, Gm1313 antikoerper, Ifi210 antikoerper, absent in melanoma 2 antikoerper, AIM2 antikoerper, Aim2 antikoerper
- Hintergrund
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Description: Involved in innate immune response by recognizing cytosolic double-stranded DNA and inducing caspase-1-activating inflammasome formation in macrophages. Upon binding to DNA is thought to undergo oligomerization and to associate with PYCARD initiating the recruitment of caspase-1 precusrsor and processing of interleukin-1 beta and interleukin-18. Detects cytosolic dsDNA of viral and bacterial origin in a non-sequence-specific manner. Can also trigger PYCARD-dependent, caspase-1-independent cell death that involves caspase-8 (By similarity). Tumor suppressor which may act by repressing NF-kappa-B transcriptional activity.
Gene: AIM2
- Molekulargewicht
- 39 kDa
- Gen-ID
- 9447
- UniProt
- O14862
- Pathways
- Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Inflammasome
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