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BMP10 Antikörper (Internal Region)

BMP10 Reaktivität: Human WB, ELISA, ICC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6256960
  • Target Alle BMP10 Antikörper anzeigen
    BMP10 (Bone Morphogenetic Protein 10 (BMP10))
    Bindungsspezifität
    • 15
    • 7
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reaktivität
    • 60
    • 24
    • 24
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    Human
    Wirt
    • 52
    • 7
    • 1
    • 1
    Kaninchen
    Klonalität
    • 55
    • 6
    Polyklonal
    Konjugat
    • 33
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser BMP10 Antikörper ist unkonjugiert
    Applikation
    • 47
    • 16
    • 14
    • 13
    • 8
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
    Spezifität
    BMP10 Antibody detects endogenous levels of total BMP10.
    Homologie
    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human BMP10, corresponding to a region within the internal amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product BMP10 Primärantikörper
  • Applikationshinweise
    WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    BMP10 (Bone Morphogenetic Protein 10 (BMP10))
    Andere Bezeichnung
    BMP10 (BMP10 Produkte)
    Synonyme
    BMP10 antikoerper, si:dkey-13n15.5 antikoerper, Bmp10 antikoerper, BMP9 antikoerper, BMP-10 antikoerper, bone morphogenetic protein 10 antikoerper, BMP10 antikoerper, bmp10 antikoerper, LOC662386 antikoerper, Bmp10 antikoerper
    Hintergrund

    Description: Required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Inhibits endothelial cell migration and growth. May reduce cell migration and cell matrix adhesion in breast cancer cell lines.

    Gene: BMP10

    Molekulargewicht
    48 kDa
    Gen-ID
    27302
    UniProt
    O95393
    Pathways
    Hormone Activity, Regulation of Muscle Cell Differentiation
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