BRMS1 Antikörper (N-Term)

Produktnummer ABIN6256973

Produktdetails anti-BRMS1 Antikörper

Target: BRMS1 (Breast Cancer Metastasis Suppressor 1 (BRMS1))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BRMS1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: BRMS1 Antibody detects endogenous levels of total BRMS1.

Homologie: Pig,Horse,Sheep,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human BRMS1, corresponding to a region within N-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu BRMS1

Target: BRMS1 (Breast Cancer Metastasis Suppressor 1 (BRMS1))

Andere Bezeichnung: BRMS1 (BRMS1 Produkte)

Synonyme: MGC98869 antikoerper, BRMS1 antikoerper, BRMS1L antikoerper, AV003220 antikoerper, AW554636 antikoerper, si:zc188c22.3 antikoerper, si:zc194c5.2 antikoerper, wu:fb57b08 antikoerper, zgc:56414 antikoerper, breast cancer metastasis suppressor 1 antikoerper, breast cancer metastasis-suppressor 1 antikoerper, breast cancer metastasis suppressor 1 L homeolog antikoerper, BRMS1 antikoerper, Brms1 antikoerper, brms1.L antikoerper, brms1 antikoerper

Hintergrund:

Description: Transcriptional repressor. Down-regulates transcription activation by NF-kappa-B by promoting the deacetylation of RELA at 'Lys-310'. Promotes HDAC1 binding to promoter regions. Down-regulates expression of anti-apoptotic genes that are controlled by NF-kappa-B. Promotes apoptosis in cells that have inadequate adherence to a substrate, a process called anoikis, and may thereby inhibit metastasis. May be a mediator of metastasis suppression in breast carcinoma.

Gene: BRMS1

Molekulargewicht: 28 kDa

Gen-ID: 25855

UniProt: Q9HCU9