PFKL Antikörper (C-Term)
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- Target Alle PFKL Antikörper anzeigen
- PFKL (Phosphofructokinase, Liver (PFKL))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PFKL Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Spezifität
- K6PL Antibody detects endogenous levels of total K6PL.
- Homologie
- Pig,Bovine,Horse,Sheep,Dog,Chicken
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human K6PL, corresponding to a region within C-terminal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product PFKL Primärantikörper
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anti-Phosphofructokinase, Liver (PFKL) (Center) antibody
PFKL Reaktivität: Human, Maus WB, IHC (p), IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Phosphofructokinase, Liver (PFKL) (AA 229-479) antibodyPFKL Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Phosphofructokinase, Liver (PFKL) (AA 669-699), (C-Term) antibodyPFKL Reaktivität: Human, Maus WB, IHC (p) Wirt: Kaninchen Polyclonal RB03903 unconjugated
anti-Phosphofructokinase, Liver (PFKL) (AA 700-780) antibodyPFKL Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Phosphofructokinase, Liver (PFKL) (Middle Region) antibodyPFKL Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Schaf, Zebrafisch (Danio rerio) WB Wirt: Kaninchen Polyclonal unconjugated
anti-Phosphofructokinase, Liver (PFKL) (C-Term) antibodyPFKL Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Phosphofructokinase, Liver (PFKL) (C-Term) antibodyPFKL Reaktivität: Human, Maus, Ratte WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Phosphofructokinase, Liver (PFKL) (AA 371-399) antibodyPFKL Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB6851 unconjugated
anti-Phosphofructokinase, Liver (PFKL) (AA 441-540) antibodyPFKL Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 2A9 unconjugated
anti-Phosphofructokinase, Liver (PFKL) (AA 1-827) antibodyPFKL Reaktivität: Human WB Wirt: Maus Polyclonal unconjugated
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- Applikationshinweise
- WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- PFKL (Phosphofructokinase, Liver (PFKL))
- Andere Bezeichnung
- PFKL (PFKL Produkte)
- Synonyme
- PFK-B antikoerper, AA407869 antikoerper, phosphofructokinase, liver type antikoerper, phosphofructokinase, liver, B-type antikoerper, PFKL antikoerper, Pfkl antikoerper
- Hintergrund
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Description: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis (PubMed:22923583). Negatively regulates the phagocyte oxidative burst in response to bacterial infection by controlling cellular NADPH biosynthesis and NADPH oxidase-derived reactive oxygen species. Upon macrophage activation, drives the metabolic switch toward glycolysis, thus preventing glucose turnover that produces NADPH via pentose phosphate pathway (By similarity).
Gene: PFKL
- Molekulargewicht
- 85 kDa
- Gen-ID
- 5211
- UniProt
- P17858
- Pathways
- Negative Regulation of Hormone Secretion, Warburg Effekt
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