ADCY6 Antikörper (Internal Region)

Produktnummer ABIN6257031

Produktdetails anti-ADCY6 Antikörper

Target: ADCY6 (Adenylate Cyclase 6 (ADCY6))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ADCY6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)

Spezifität: ADCY5/6 Antibody detects endogenous levels of total ADCY5/6.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human ADCY5/6, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu ADCY6

Target: ADCY6 (Adenylate Cyclase 6 (ADCY6))

Andere Bezeichnung: ADCY5,ADCY6 (ADCY6 Produkte)

Synonyme: ADCY6 antikoerper, adcy6 antikoerper, AC6 antikoerper, mKIAA0422 antikoerper, ACVI antikoerper, ADCYB antikoerper, adenylate cyclase 6 L homeolog antikoerper, adenylate cyclase 6 antikoerper, adenylate cyclase 6a antikoerper, adcy6.L antikoerper, ADCY6 antikoerper, adcy6a antikoerper, adcy6 antikoerper, Adcy6 antikoerper

Hintergrund:

Description: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling (PubMed:15385642, PubMed:26206488, PubMed:24700542). Mediates signaling downstream of ADRB1 (PubMed:24700542). Regulates the increase of free cytosolic Ca2+ in response to increased blood glucose levels and contributes to the regulation of Ca2+-dependent insulin secretion (PubMed:24740569).

Gene: ADCY5

Molekulargewicht: 138 kDa

Gen-ID: 111, 112

UniProt: O95622, O43306

Pathways: EGFR Signaling Pathway, Neurotrophin Signalübertragung, Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma