CNOT7 Antikörper (C-Term)

Produktnummer ABIN6257033

Produktdetails anti-CNOT7 Antikörper

Target: CNOT7 (CCR4-NOT Transcription Complex, Subunit 7 (CNOT7))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CNOT7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: CNOT7 Antibody detects endogenous levels of total CNOT7.

Homologie: Pig,Bovine,Horse,Sheep,Dog,Chicken,Xenopus

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human CNOT7, corresponding to a region within C-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu CNOT7

Target: CNOT7 (CCR4-NOT Transcription Complex, Subunit 7 (CNOT7))

Andere Bezeichnung: CNOT7 (CNOT7 Produkte)

Synonyme: CNOT7 antikoerper, CAF1 antikoerper, fd59c07 antikoerper, fj07d05 antikoerper, wu:fd59c07 antikoerper, wu:fj07d05 antikoerper, zgc:153168 antikoerper, caf1 antikoerper, Caf1a antikoerper, hCAF-1 antikoerper, AU022737 antikoerper, CAF-1 antikoerper, Caf1 antikoerper, Pop2 antikoerper, CCR4-NOT transcription complex subunit 7 antikoerper, ccr4-not transcription complex, subunit 7 antikoerper, CCR4-NOT transcription complex, subunit 7 antikoerper, ccr4-not transcription complex, subunit 7, putative antikoerper, CCR4-NOT transcription complex subunit 7 S homeolog antikoerper, CNOT7 antikoerper, CNL04550 antikoerper, GL50803_10606 antikoerper, GL50803_8209 antikoerper, CGB_D2510C antikoerper, cnot7 antikoerper, cnot7.S antikoerper, Cnot7 antikoerper

Hintergrund:

Description: Has 3'-5' poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate. Its function seems to be partially redundant with that of CNOT8. Catalytic component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. During miRNA-mediated repression the complex seems also to act as translational repressor during translational initiation. Additional complex functions may be a consequence of its influence on mRNA expression. Associates with members of the BTG family such as TOB1 and BTG2 and is required for their anti-proliferative activity.

Gene: CNOT7

Molekulargewicht: 36 kDa

Gen-ID: 29883

UniProt: Q9UIV1

Pathways: Ribonucleoprotein Complex Subunit Organization