ARHGAP17 Antikörper (Internal Region)

Produktnummer ABIN6257043

Produktdetails anti-ARHGAP17 Antikörper

Target: ARHGAP17 (rho GTPase Activating Protein 17 (ARHGAP17))

Bindungsspezifität: Internal Region

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARHGAP17 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: RHG17 Antibody detects endogenous levels of total RHG17.

Homologie: Bovine,Horse,Rabbit,Dog,Xenopus

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human RHG17, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu ARHGAP17

Target: ARHGAP17 (rho GTPase Activating Protein 17 (ARHGAP17))

Andere Bezeichnung: ARHGAP17 (ARHGAP17 Produkte)

Synonyme: MST066 antikoerper, MST110 antikoerper, MSTP038 antikoerper, MSTP066 antikoerper, MSTP110 antikoerper, NADRIN antikoerper, PP367 antikoerper, PP4534 antikoerper, RICH1 antikoerper, RICH1B antikoerper, WBP15 antikoerper, 5730403H17Rik antikoerper, Nadrin antikoerper, Nadrin2 antikoerper, Rich1 antikoerper, Wbp15 antikoerper, Rho GTPase activating protein 17 antikoerper, ARHGAP17 antikoerper, arhgap17 antikoerper, Arhgap17 antikoerper

Hintergrund:

Description: Rho GTPase-activating protein involved in the maintenance of tight junction by regulating the activity of CDC42, thereby playing a central role in apical polarity of epithelial cells. Specifically acts as a GTPase activator for the CDC42 GTPase by converting it to an inactive GDP-bound state. The complex formed with AMOT acts by regulating the uptake of polarity proteins at tight junctions, possibly by deciding whether tight junction transmembrane proteins are recycled back to the plasma membrane or sent elsewhere. Participates in the Ca2+-dependent regulation of exocytosis, possibly by catalyzing GTPase activity of Rho family proteins and by inducing the reorganization of the cortical actin filaments. Acts as a GTPase activator in vitro for RAC1.

Gene: ARHGAP17

Molekulargewicht: 100 kDa

Gen-ID: 55114

UniProt: Q68EM7