ERCC5 Antikörper (N-Term)

Produktnummer ABIN6257134

Produktdetails anti-ERCC5 Antikörper

Target: ERCC5 (DNA Repair Protein Complementing XP-G Cells (ERCC5))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ERCC5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: ERCC5 Antibody detects endogenous levels of total ERCC5.

Homologie: Bovine,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human ERCC5, corresponding to a region within N-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu ERCC5

Target: ERCC5 (DNA Repair Protein Complementing XP-G Cells (ERCC5))

Andere Bezeichnung: ERCC5 (ERCC5 Produkte)

Synonyme: COFS3 antikoerper, ERCM2 antikoerper, UVDR antikoerper, XPG antikoerper, XPGC antikoerper, cofs3 antikoerper, ercm2 antikoerper, uvdr antikoerper, xpg antikoerper, xpgc antikoerper, Xpg antikoerper, ERCC excision repair 5, endonuclease antikoerper, excision repair cross-complementation group 5 L homeolog antikoerper, excision repair cross-complementing rodent repair deficiency, complementation group 5 antikoerper, ERCC5 antikoerper, ercc5.L antikoerper, Ercc5 antikoerper

Hintergrund:

Description: Single-stranded structure-specific DNA endonuclease involved in DNA excision repair. Makes the 3'incision in DNA nucleotide excision repair (NER). Acts as a cofactor for a DNA glycosylase that removes oxidized pyrimidines from DNA. May also be involved in transcription-coupled repair of this kind of damage, in transcription by RNA polymerase II, and perhaps in other processes too.

Gene: ERCC5

Molekulargewicht: 130 kDa

Gen-ID: 2073

UniProt: P28715

Pathways: DNA Reparatur