INTS6 Antikörper (C-Term)
-
- Target Alle INTS6 Antikörper anzeigen
- INTS6 (Integrator Complex Subunit 6 (INTS6))
-
Bindungsspezifität
- C-Term
-
Reaktivität
- Human, Maus
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser INTS6 Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB), ELISA
- Spezifität
- INT6 Antibody detects endogenous levels of total INT6.
- Homologie
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human INT6, corresponding to a region within C-terminal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product INTS6 Primärantikörper
-
-
- Applikationshinweise
- WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Haltbarkeit
- 12 months
-
- Target
- INTS6 (Integrator Complex Subunit 6 (INTS6))
- Andere Bezeichnung
- INTS6 (INTS6 Produkte)
- Hintergrund
-
Description: Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable). Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex (PubMed:23904267). May have a tumor suppressor role, an ectopic expression suppressing tumor cell growth (PubMed:15254679, PubMed:16239144).
Gene: INTS6
- Molekulargewicht
- 117 kDa
- Gen-ID
- 26512
- UniProt
- Q9UL03
-