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INTS6 Antikörper (C-Term)

INTS6 Reaktivität: Human, Maus WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6257160
  • Target Alle INTS6 Antikörper anzeigen
    INTS6 (Integrator Complex Subunit 6 (INTS6))
    Bindungsspezifität
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 26
    • 11
    • 10
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    Human, Maus
    Wirt
    • 24
    • 2
    Kaninchen
    Klonalität
    • 24
    • 2
    Polyklonal
    Konjugat
    • 15
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser INTS6 Antikörper ist unkonjugiert
    Applikation
    • 12
    • 7
    • 6
    • 6
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA
    Spezifität
    INT6 Antibody detects endogenous levels of total INT6.
    Homologie
    Pig,Bovine,Horse,Sheep,Rabbit,Dog
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human INT6, corresponding to a region within C-terminal amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product INTS6 Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Haltbarkeit
    12 months
  • Target
    INTS6 (Integrator Complex Subunit 6 (INTS6))
    Andere Bezeichnung
    INTS6 (INTS6 Produkte)
    Hintergrund

    Description: Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable). Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex (PubMed:23904267). May have a tumor suppressor role, an ectopic expression suppressing tumor cell growth (PubMed:15254679, PubMed:16239144).

    Gene: INTS6

    Molekulargewicht
    117 kDa
    Gen-ID
    26512
    UniProt
    Q9UL03
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