INTS6 Antikörper (C-Term)

Produktnummer ABIN6257160

Produktdetails anti-INTS6 Antikörper

Target: INTS6 (Integrator Complex Subunit 6 (INTS6))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser INTS6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Spezifität: INT6 Antibody detects endogenous levels of total INT6.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human INT6, corresponding to a region within C-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu INTS6

Target: INTS6 (Integrator Complex Subunit 6 (INTS6))

Andere Bezeichnung: INTS6 (INTS6 Produkte)

Synonyme: DBI-1 antikoerper, DDX26 antikoerper, DDX26A antikoerper, DICE1 antikoerper, HDB antikoerper, INT6 antikoerper, Notchl2 antikoerper, EIF3-P48 antikoerper, EIF3S6 antikoerper, eIF3-p46 antikoerper, 2900075H24Rik antikoerper, AI480962 antikoerper, Ddx26 antikoerper, Notch2l antikoerper, LRRGT00024 antikoerper, ints6 antikoerper, zgc:63527 antikoerper, INTS6 antikoerper, ints6-b antikoerper, Int6-A antikoerper, dbi-1 antikoerper, ddx26 antikoerper, ddx26a antikoerper, dice1 antikoerper, hdb antikoerper, int6 antikoerper, ints6-a antikoerper, notchl2 antikoerper, integrator complex subunit 6 antikoerper, eukaryotic translation initiation factor 3 subunit E antikoerper, integrator complex subunit 6 like antikoerper, integrator complex subunit 6 S homeolog antikoerper, integrator complex subunit 6 L homeolog antikoerper, INTS6 antikoerper, EIF3E antikoerper, Ints6 antikoerper, ints6l antikoerper, ints6 antikoerper, ints6.S antikoerper, Tsp_09465 antikoerper, LOC100164318 antikoerper, ints6.L antikoerper

Hintergrund:

Description: Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable). Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex (PubMed:23904267). May have a tumor suppressor role, an ectopic expression suppressing tumor cell growth (PubMed:15254679, PubMed:16239144).

Gene: INTS6

Molekulargewicht: 117 kDa

Gen-ID: 26512

UniProt: Q9UL03