FOXN4 Antikörper (C-Term)
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- Target Alle FOXN4 Antikörper anzeigen
- FOXN4 (Forkhead Box N4 (FOXN4))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser FOXN4 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- Spezifität
- FOXN4 Antibody detects endogenous levels of total FOXN4.
- Homologie
- Pig,Bovine,Sheep,Xenopus
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human FOXN4, corresponding to a region within C-terminal amino acids.
- Isotyp
- IgG
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- Applikationshinweise
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- FOXN4 (Forkhead Box N4 (FOXN4))
- Andere Bezeichnung
- FOXN4 (FOXN4 Produkte)
- Synonyme
- whn antikoerper, whna antikoerper, forkhead box N4 antikoerper, forkhead box N4 S homeolog antikoerper, FOXN4 antikoerper, foxn4 antikoerper, Foxn4 antikoerper, foxn4.S antikoerper
- Hintergrund
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Description: Transcription factor essential for neural and some non-neural tissues development, such as retina and lung respectively. Binds to an 11-bp consensus sequence containing the invariant tetranucleotide 5'-ACGC-3'. During development of the central nervous system, is required to specify the amacrine and horizontal cell fates from multipotent retinal progenitors while suppressing the alternative photoreceptor cell fates through activating DLL4-NOTCH signaling. Also acts synergistically with ASCL1/MASH1 to activate DLL4-NOTCH signaling and drive commitment of p2 progenitors to the V2b interneuron fates during spinal cord neurogenesis. In development of non-neural tissues, plays an essential role in the specification of the atrioventricular canal and is indirectly required for patterning the distal airway during lung development (By similarity).
Gene: FOXN4
- Molekulargewicht
- 50 kDa
- Gen-ID
- 121643
- UniProt
- Q96NZ1
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