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FOXN4 Antikörper (C-Term)

FOXN4 Reaktivität: Human WB, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6257195
  • Target Alle FOXN4 Antikörper anzeigen
    FOXN4 (Forkhead Box N4 (FOXN4))
    Bindungsspezifität
    • 13
    • 7
    • 7
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 43
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 43
    Kaninchen
    Klonalität
    • 43
    Polyklonal
    Konjugat
    • 19
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser FOXN4 Antikörper ist unkonjugiert
    Applikation
    • 33
    • 26
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Spezifität
    FOXN4 Antibody detects endogenous levels of total FOXN4.
    Homologie
    Pig,Bovine,Sheep,Xenopus
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human FOXN4, corresponding to a region within C-terminal amino acids.
    Isotyp
    IgG
  • Applikationshinweise
    WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    FOXN4 (Forkhead Box N4 (FOXN4))
    Andere Bezeichnung
    FOXN4 (FOXN4 Produkte)
    Synonyme
    whn antikoerper, whna antikoerper, forkhead box N4 antikoerper, forkhead box N4 S homeolog antikoerper, FOXN4 antikoerper, foxn4 antikoerper, Foxn4 antikoerper, foxn4.S antikoerper
    Hintergrund

    Description: Transcription factor essential for neural and some non-neural tissues development, such as retina and lung respectively. Binds to an 11-bp consensus sequence containing the invariant tetranucleotide 5'-ACGC-3'. During development of the central nervous system, is required to specify the amacrine and horizontal cell fates from multipotent retinal progenitors while suppressing the alternative photoreceptor cell fates through activating DLL4-NOTCH signaling. Also acts synergistically with ASCL1/MASH1 to activate DLL4-NOTCH signaling and drive commitment of p2 progenitors to the V2b interneuron fates during spinal cord neurogenesis. In development of non-neural tissues, plays an essential role in the specification of the atrioventricular canal and is indirectly required for patterning the distal airway during lung development (By similarity).

    Gene: FOXN4

    Molekulargewicht
    50 kDa
    Gen-ID
    121643
    UniProt
    Q96NZ1
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