IFNAR2 Antikörper (C-Term)
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- Target Alle IFNAR2 Antikörper anzeigen
- IFNAR2 (Interferon alpha/beta Receptor 2 (IFNAR2))
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Bindungsspezifität
- C-Term
- Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser IFNAR2 Antikörper ist unkonjugiert
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Applikation
- ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
- Spezifität
- IFNAR2 Antibody detects endogenous levels of total IFNAR2.
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human IFNAR2, corresponding to a region within C-terminal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product IFNAR2 Primärantikörper
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- Applikationshinweise
- WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Haltbarkeit
- 12 months
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- Target
- IFNAR2 (Interferon alpha/beta Receptor 2 (IFNAR2))
- Andere Bezeichnung
- IFNAR2 (IFNAR2 Produkte)
- Synonyme
- AI747302 antikoerper, Ifnar-2 antikoerper, IFN-R antikoerper, IFN-alpha-REC antikoerper, IFNABR antikoerper, IFNARB antikoerper, IFN-R-2 antikoerper, IFNBR antikoerper, interferon alpha and beta receptor subunit 2 antikoerper, interferon (alpha and beta) receptor 2 antikoerper, IFNAR2 antikoerper, Ifnar2 antikoerper
- Hintergrund
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Description: Associates with IFNAR1 to form the type I interferon receptor. Receptor for interferons alpha and beta. Involved in IFN-mediated STAT1, STAT2 and STAT3 activation (PubMed:26424569). Isoform 1 and isoform 2 are directly involved in signal transduction due to their association with the TYR kinase, JAK1 (PubMed:8181059, PubMed:7665574, PubMed:7759950). Isoform 3 is a potent inhibitor of type I IFN receptor activity (PubMed:7759950).
Gene: IFNAR2
- Gen-ID
- 3455
- UniProt
- P48551
- Pathways
- JAK-STAT Signalweg, Hepatitis C
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