GDF15 Antikörper (N-Term)
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- Target Alle GDF15 Antikörper anzeigen
- GDF15 (Growth Differentiation Factor 15 (GDF15))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser GDF15 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
- Spezifität
- GDF15 Antibody detects endogenous levels of total GDF15.
- Homologie
- Pig,Bovine,Sheep,Dog
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human GDF15, corresponding to a region within N-terminal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product GDF15 Primärantikörper
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anti-Growth Differentiation Factor 15 (GDF15) (AA 49-308) antibody
GDF15 Reaktivität: Human WB, IHC, IP, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Growth Differentiation Factor 15 (GDF15) (C-Term) antibodyVerified GDF15 Reaktivität: Human WB, ELISA, IHC, FACS Wirt: Ziege Polyclonal unconjugated
anti-Growth Differentiation Factor 15 (GDF15) (C-Term) antibody (Biotin)GDF15 Reaktivität: Human, Maus WB, ELISA Wirt: Kaninchen Polyclonal Biotin
anti-Growth Differentiation Factor 15 (GDF15) (AA 51-79) antibodyGDF15 Reaktivität: Human WB, ELISA, IHC, FACS Wirt: Kaninchen Polyclonal unconjugated
anti-Growth Differentiation Factor 15 (GDF15) (AA 30-308) antibodyGDF15 Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Growth Differentiation Factor 15 (GDF15) (AA 221-308) antibodyGDF15 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Growth Differentiation Factor 15 (GDF15) (AA 51-79), (N-Term) antibodyGDF15 Reaktivität: Human WB, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB30209 unconjugated
anti-Growth Differentiation Factor 15 (GDF15) (C-Term) antibody (HRP)GDF15 Reaktivität: Human, Maus WB, ELISA Wirt: Kaninchen Polyclonal HRP
anti-Growth Differentiation Factor 15 (GDF15) (AA 195-308) antibodyGDF15 Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Growth Differentiation Factor 15 (GDF15) (AA 198-308) antibodyGDF15 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- GDF15 (Growth Differentiation Factor 15 (GDF15))
- Andere Bezeichnung
- GDF15 (GDF15 Produkte)
- Synonyme
- GDF15 antikoerper, GDF-15 antikoerper, MIC-1 antikoerper, MIC1 antikoerper, NAG-1 antikoerper, PDF antikoerper, PLAB antikoerper, PTGFB antikoerper, SBF antikoerper, growth differentiation factor 15 antikoerper, GDF15 antikoerper, Gdf15 antikoerper
- Hintergrund
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Description: Regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses (PubMed:28953886, PubMed:28846097, PubMed:28846098, PubMed:28846099, PubMed:23468844, PubMed:29046435). Binds to its receptor, GFRAL, and activates GFRAL-expressing neurons localized in the area postrema and nucleus tractus solitarius of the brainstem (PubMed:28953886, PubMed:28846097, PubMed:28846098, PubMed:28846099). It then triggers the activation of neurons localized within the parabrachial nucleus and central amygdala, which contitutes part of the 'emergency circuit' that shapes feeding responses to stressful conditions (PubMed:28953886). On hepatocytes, inhibits growth hormone signaling (By similarity).
Gene: GDF15
- Molekulargewicht
- 37 kDa
- Gen-ID
- 9518
- UniProt
- Q99988
- Pathways
- SARS-CoV-2 Protein Interaktom
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