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XRN1 Antikörper (N-Term)

XRN1 Reaktivität: Human, Maus WB, ICC, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6257273
  • Target Alle XRN1 Antikörper anzeigen
    XRN1 (5'-3' Exoribonuclease 1 (XRN1))
    Bindungsspezifität
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 18
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 18
    • 1
    Kaninchen
    Klonalität
    • 18
    • 1
    Polyklonal
    Konjugat
    • 12
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser XRN1 Antikörper ist unkonjugiert
    Applikation
    • 12
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunocytochemistry (ICC), ELISA, Immunofluorescence (IF)
    Spezifität
    XRN1 Antibody detects endogenous levels of total XRN1.
    Homologie
    Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human XRN1, corresponding to a region within N-terminal amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product XRN1 Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Haltbarkeit
    12 months
  • Target
    XRN1 (5'-3' Exoribonuclease 1 (XRN1))
    Andere Bezeichnung
    XRN1 (XRN1 Produkte)
    Synonyme
    wu:fk92c07 antikoerper, zgc:63635 antikoerper, SEP1 antikoerper, Dhm2 antikoerper, exo antikoerper, mXrn1 antikoerper, RGD1309713 antikoerper, 5'-3' exoribonuclease 1 antikoerper, xrn1 antikoerper, XRN1 antikoerper, Tsp_05930 antikoerper, Xrn1 antikoerper
    Hintergrund

    Description: Major 5'-3' exoribonuclease involved in mRNA decay. Required for the 5'-3'-processing of the G4 tetraplex-containing DNA and RNA substrates. The kinetic of hydrolysis is faster for G4 RNA tetraplex than for G4 DNA tetraplex and monomeric RNA tetraplex. Binds to RNA and DNA (By similarity). Plays a role in replication-dependent histone mRNA degradation. May act as a tumor suppressor protein in osteogenic sarcoma (OGS).

    Gene: XRN1

    Molekulargewicht
    194 kDa
    Gen-ID
    54464
    UniProt
    Q8IZH2
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