ING4 Antikörper (Internal Region)
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- Target Alle ING4 Antikörper anzeigen
- ING4 (Inhibitor of Growth Family, Member 4 (ING4))
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Bindungsspezifität
- Internal Region
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ING4 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- Spezifität
- ING4 Antibody detects endogenous levels of total ING4.
- Homologie
- Bovine,Horse,Sheep,Rabbit,Dog,Chicken
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human ING4, corresponding to a region within the internal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product ING4 Primärantikörper
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anti-Inhibitor of Growth Family, Member 4 (ING4) (AA 1-249) antibody
ING4 Reaktivität: Human WB, IP, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Inhibitor of Growth Family, Member 4 (ING4) (AA 1-249) antibodyING4 Reaktivität: Human WB, IHC (p) Wirt: Maus Polyclonal unconjugated
anti-Inhibitor of Growth Family, Member 4 (ING4) (AA 162-195), (C-Term) antibodyING4 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB47839 unconjugated
anti-Inhibitor of Growth Family, Member 4 (ING4) (AA 1-249) antibodyING4 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 8F7 unconjugated
anti-Inhibitor of Growth Family, Member 4 (ING4) (AA 164-175), (Isoform 1) antibodyING4 Reaktivität: Human WB, ELISA Wirt: Ziege Polyclonal unconjugated
anti-Inhibitor of Growth Family, Member 4 (ING4) (AA 1-190) antibodyING4 Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Inhibitor of Growth Family, Member 4 (ING4) (AA 110-159) antibodyING4 Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Kaninchen, Affe, Schwein WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Inhibitor of Growth Family, Member 4 (ING4) (AA 75-249) antibodyING4 Reaktivität: Human ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Inhibitor of Growth Family, Member 4 (ING4) (Internal Region) antibodyING4 Reaktivität: Human, Maus, Ratte WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Haltbarkeit
- 12 months
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- Target
- ING4 (Inhibitor of Growth Family, Member 4 (ING4))
- Andere Bezeichnung
- ING4 (ING4 Produkte)
- Hintergrund
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Description: Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Through chromatin acetylation it may function in DNA replication. May inhibit tumor progression by modulating the transcriptional output of signaling pathways which regulate cell proliferation. Can suppress brain tumor angiogenesis through transcriptional repression of RELA/NFKB3 target genes when complexed with RELA. May also specifically suppress loss of contact inhibition elicited by activated oncogenes such as MYC. Represses hypoxia inducible factor's (HIF) activity by interacting with HIF prolyl hydroxylase 2 (EGLN1). Can enhance apoptosis induced by serum starvation in mammary epithelial cell line HC11 (By similarity).
Gene: ING4
- Molekulargewicht
- 29 kDa
- Gen-ID
- 51147
- UniProt
- Q9UNL4
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