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IL-11 Antikörper (N-Term)

IL11 Reaktivität: Human, Maus, Ratte WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6257286
  • Target Alle IL-11 (IL11) Antikörper anzeigen
    IL-11 (IL11) (Interleukin 11 (IL11))
    Bindungsspezifität
    • 15
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    Human, Maus, Ratte
    Wirt
    • 47
    • 19
    • 1
    • 1
    Kaninchen
    Klonalität
    • 48
    • 20
    Polyklonal
    Konjugat
    • 33
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser IL-11 Antikörper ist unkonjugiert
    Applikation
    • 47
    • 34
    • 17
    • 13
    • 13
    • 10
    • 6
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA
    Spezifität
    IL11 Antibody detects endogenous levels of total IL11.
    Homologie
    Pig,Bovine,Horse,Dog
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human IL11, corresponding to a region within N-terminal amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product IL11 Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Haltbarkeit
    12 months
  • Target
    IL-11 (IL11) (Interleukin 11 (IL11))
    Andere Bezeichnung
    IL11 (IL11 Produkte)
    Synonyme
    IL11 antikoerper, AGIF antikoerper, IL-11 antikoerper, Il-11 antikoerper, interleukin 11 antikoerper, IL11 antikoerper, Il11 antikoerper
    Hintergrund

    Description: Cytokine that stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production (PubMed:2145578). Also promotes the proliferation of hepatocytes in response to liver damage. Binding to its receptor formed by IL6ST and either IL11RA1 or IL11RA2 activates a signaling cascade that promotes cell proliferation (PubMed:12919066). Signaling leads to the activation of intracellular protein kinases and the phosphorylation of STAT3.

    Gene: IL11

    Molekulargewicht
    27 kDa
    Gen-ID
    3589
    UniProt
    P20809
    Pathways
    JAK-STAT Signalweg, Negative Regulation of Hormone Secretion
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