IL-11 Antikörper (N-Term)
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- Target Alle IL-11 (IL11) Antikörper anzeigen
- IL-11 (IL11) (Interleukin 11 (IL11))
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Bindungsspezifität
- N-Term
- Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser IL-11 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Spezifität
- IL11 Antibody detects endogenous levels of total IL11.
- Homologie
- Pig,Bovine,Horse,Dog
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human IL11, corresponding to a region within N-terminal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product IL11 Primärantikörper
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- Applikationshinweise
- WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Haltbarkeit
- 12 months
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- Target
- IL-11 (IL11) (Interleukin 11 (IL11))
- Andere Bezeichnung
- IL11 (IL11 Produkte)
- Synonyme
- IL11 antikoerper, AGIF antikoerper, IL-11 antikoerper, Il-11 antikoerper, interleukin 11 antikoerper, IL11 antikoerper, Il11 antikoerper
- Hintergrund
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Description: Cytokine that stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production (PubMed:2145578). Also promotes the proliferation of hepatocytes in response to liver damage. Binding to its receptor formed by IL6ST and either IL11RA1 or IL11RA2 activates a signaling cascade that promotes cell proliferation (PubMed:12919066). Signaling leads to the activation of intracellular protein kinases and the phosphorylation of STAT3.
Gene: IL11
- Molekulargewicht
- 27 kDa
- Gen-ID
- 3589
- UniProt
- P20809
- Pathways
- JAK-STAT Signalweg, Negative Regulation of Hormone Secretion
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