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MDFI Antikörper (Internal Region)

MDFI Reaktivität: Human, Ratte, Maus ELISA, WB, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6257357
  • Target Alle MDFI Antikörper anzeigen
    MDFI (MyoD Family Inhibitor (MDFI))
    Bindungsspezifität
    • 15
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reaktivität
    • 33
    • 9
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Ratte, Maus
    Wirt
    • 30
    • 2
    • 2
    Kaninchen
    Klonalität
    • 33
    • 1
    Polyklonal
    Konjugat
    • 13
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MDFI Antikörper ist unkonjugiert
    Applikation
    • 13
    • 13
    • 11
    • 10
    • 3
    • 3
    • 2
    • 2
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Spezifität
    MDFI Antibody detects endogenous levels of total MDFI.
    Homologie
    Pig,Bovine,Horse,Sheep,Dog
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human MDFI, corresponding to a region within the internal amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product MDFI Primärantikörper
  • Applikationshinweise
    WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    MDFI (MyoD Family Inhibitor (MDFI))
    Andere Bezeichnung
    MDFI (MDFI Produkte)
    Synonyme
    MDFI antikoerper, I-MF antikoerper, I-mfa antikoerper, I-mf antikoerper, RGD1560271 antikoerper, MyoD family inhibitor antikoerper, MDFI antikoerper, Mdfi antikoerper
    Hintergrund

    Description: Inhibits the transactivation activity of the Myod family of myogenic factors and represses myogenesis. Acts by associating with Myod family members and retaining them in the cytoplasm by masking their nuclear localization signals. Can also interfere with the DNA-binding activity of Myod family members. Plays an important role in trophoblast and chondrogenic differentiation. Regulates the transcriptional activity of TCF7L1/TCF3 by interacting directly with TCF7L1/TCF3 and preventing it from binding DNA. Binds to the axin complex, resulting in an increase in the level of free beta-catenin. Affects axin regulation of the WNT and JNK signaling pathways (By similarity).

    Gene: MDFI

    Molekulargewicht
    25 kDa
    Gen-ID
    4188
    UniProt
    Q99750
    Pathways
    Maintenance of Protein Location
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