PNN Antikörper (Internal Region)

Produktnummer ABIN6257423

Produktdetails anti-PNN Antikörper

Target: PNN (Pinin, Desmosome Associated Protein (PNN))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PNN Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: PNN Antibody detects endogenous levels of total PNN.

Homologie: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human PNN, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu PNN

Target: PNN (Pinin, Desmosome Associated Protein (PNN))

Andere Bezeichnung: PNN (PNN Produkte)

Synonyme: DRS antikoerper, DRSP antikoerper, SDK3 antikoerper, memA antikoerper, wu:fb24d03 antikoerper, pnn antikoerper, MGC88923 antikoerper, PNN antikoerper, AU045199 antikoerper, D12Ertd512e antikoerper, CG8383 antikoerper, Dmel\\CG8383 antikoerper, dPnn antikoerper, pinin, desmosome associated protein antikoerper, pinin antikoerper, Pinin antikoerper, PNN antikoerper, Pnn antikoerper, pnn antikoerper, LOC100380709 antikoerper

Hintergrund:

Description: Transcriptional activator binding to the E-box 1 core sequence of the E-cadherin promoter gene, the core-binding sequence is 5'CAGGTG-3'. Capable of reversing CTBP1-mediated transcription repression. Auxiliary component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Participates in the regulation of alternative pre-mRNA splicing. Associates to spliced mRNA within 60 nt upstream of the 5'-splice sites. Component of the PSAP complex which binds RNA in a sequence-independent manner and is proposed to be recruited to the EJC prior to or during the splicing process and to regulate specific excision of introns in specific transcription subsets. Involved in the establishment and maintenance of epithelia cell-cell adhesion. Potential tumor suppressor for renal cell carcinoma.

Gene: PNN

Molekulargewicht: 85 kDa

Gen-ID: 5411

UniProt: Q9H307