RRM2B Antikörper (N-Term)
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- Target Alle RRM2B Antikörper anzeigen
- RRM2B (Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Ratte, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser RRM2B Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- Spezifität
- RRM2B Antibody detects endogenous levels of total RRM2B.
- Homologie
- Bovine,Sheep,Dog
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human RRM2B, corresponding to a region within N-terminal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product RRM2B Primärantikörper
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anti-Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B) (AA 3-84) antibody
RRM2B Reaktivität: Human WB, ELISA, IF Wirt: Maus Monoclonal 6C1 unconjugated
anti-Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B) (AA 1-351) antibodyRRM2B Reaktivität: Human WB, ELISA, IHC, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B) (N-Term) antibodyRRM2B Reaktivität: Human WB, ELISA, IHC, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B) (AA 128-157) antibodyRRM2B Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB36901 unconjugated
anti-Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B) (AA 3-84) antibodyRRM2B Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 6C1 unconjugated
anti-Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B) (C-Term) antibodyRRM2B Reaktivität: Human, Ratte, Maus WB Wirt: Kaninchen Polyclonal unconjugated
anti-Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B) (AA 2-17), (N-Term) antibodyRRM2B Reaktivität: Human, Ratte, Maus WB, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- RRM2B (Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B))
- Andere Bezeichnung
- RRM2B (RRM2B Produkte)
- Hintergrund
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Description: Plays a pivotal role in cell survival by repairing damaged DNA in a p53/TP53-dependent manner. Supplies deoxyribonucleotides for DNA repair in cells arrested at G1 or G2. Contains an iron-tyrosyl free radical center required for catalysis. Forms an active ribonucleotide reductase (RNR) complex with RRM1 which is expressed both in resting and proliferating cells in response to DNA damage.
Gene: RRM2B
- Molekulargewicht
- 40 kDa
- Gen-ID
- 50484
- UniProt
- Q7LG56
- Pathways
- p53 Signalweg, Negative Regulation of intrinsic apoptotic Signaling
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