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RRM2B Antikörper (N-Term)

RRM2B Reaktivität: Human, Ratte, Maus WB, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6257482
  • Target Alle RRM2B Antikörper anzeigen
    RRM2B (Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B))
    Bindungsspezifität
    • 15
    • 7
    • 6
    • 6
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 36
    • 33
    • 17
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Ratte, Maus
    Wirt
    • 48
    • 3
    Kaninchen
    Klonalität
    • 48
    • 3
    Polyklonal
    Konjugat
    • 19
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser RRM2B Antikörper ist unkonjugiert
    Applikation
    • 44
    • 22
    • 13
    • 13
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Spezifität
    RRM2B Antibody detects endogenous levels of total RRM2B.
    Homologie
    Bovine,Sheep,Dog
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human RRM2B, corresponding to a region within N-terminal amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product RRM2B Primärantikörper
  • Applikationshinweise
    WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    RRM2B (Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B))
    Andere Bezeichnung
    RRM2B (RRM2B Produkte)
    Synonyme
    p53r2 antikoerper, RRM2B antikoerper, MTDPS8A antikoerper, MTDPS8B antikoerper, P53R2 antikoerper, p53R2 antikoerper, ribonucleotide reductase M2 B (TP53 inducible) S homeolog antikoerper, ribonucleotide reductase regulatory TP53 inducible subunit M2B antikoerper, ribonucleotide reductase M2 B (TP53 inducible) antikoerper, rrm2b.S antikoerper, RRM2B antikoerper, rrm2b antikoerper, Rrm2b antikoerper
    Hintergrund

    Description: Plays a pivotal role in cell survival by repairing damaged DNA in a p53/TP53-dependent manner. Supplies deoxyribonucleotides for DNA repair in cells arrested at G1 or G2. Contains an iron-tyrosyl free radical center required for catalysis. Forms an active ribonucleotide reductase (RNR) complex with RRM1 which is expressed both in resting and proliferating cells in response to DNA damage.

    Gene: RRM2B

    Molekulargewicht
    40 kDa
    Gen-ID
    50484
    UniProt
    Q7LG56
    Pathways
    p53 Signalweg, Negative Regulation of intrinsic apoptotic Signaling
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