SF3B3 Antikörper (C-Term)
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- Target Alle SF3B3 Antikörper anzeigen
- SF3B3 (Splicing Factor 3b, Subunit 3, 130kDa (SF3B3))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SF3B3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- Spezifität
- SF3B3 Antibody detects endogenous levels of total SF3B3.
- Homologie
- Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human SF3B3, corresponding to a region within C-terminal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product SF3B3 Primärantikörper
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- Applikationshinweise
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- SF3B3 (Splicing Factor 3b, Subunit 3, 130kDa (SF3B3))
- Andere Bezeichnung
- SF3B3 (SF3B3 Produkte)
- Synonyme
- GB11574 antikoerper, rse1 antikoerper, sap130 antikoerper, sf3b130 antikoerper, staf130 antikoerper, sf3b3 antikoerper, 1810061H24Rik antikoerper, 5730409A01Rik antikoerper, AA409318 antikoerper, D8Ertd633e antikoerper, RSE1 antikoerper, SAP130 antikoerper, mKIAA0017 antikoerper, ik:tdsubc_2b2 antikoerper, wu:fb81f05 antikoerper, xx:tdsubc_2b2 antikoerper, zgc:55440 antikoerper, SF3b130 antikoerper, STAF130 antikoerper, splicing factor 3b subunit 3 antikoerper, splicing factor 3B subunit 3 antikoerper, splicing factor 3b, subunit 3, 130kDa antikoerper, splicing factor 3b subunit 3 L homeolog antikoerper, splicing factor 3b, subunit 3 antikoerper, SF3B3 antikoerper, LOC550935 antikoerper, sf3b3 antikoerper, Sf3b3 antikoerper, LOC100178056 antikoerper, sf3b3.L antikoerper
- Hintergrund
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Description: Involved in pre-mRNA splicing as a component of the splicing factor SF3B complex, a constituent of the spliceosome (PubMed:10490618, PubMed:10882114, PubMed:27720643, PubMed:28781166). SF3B complex is required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA (PubMed:12234937). May also be involved in the assembly of the 'E' complex (PubMed:10882114). Belongs also to the minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron (PubMed:15146077).
Gene: SF3B3
- Molekulargewicht
- 136 kDa
- Gen-ID
- 23450
- UniProt
- Q15393
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