SRY Antikörper (Internal Region)

Produktnummer ABIN6257506

Produktdetails anti-SRY Antikörper

Target: SRY (Sex Determining Region Y (SRY))

Bindungsspezifität: Internal Region

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SRY Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: SRY Antibody detects endogenous levels of total SRY.

Homologie: Pig,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human SRY, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu SRY

Target: SRY (Sex Determining Region Y (SRY))

Andere Bezeichnung: SRY (SRY Produkte)

Synonyme: SRXX1 antikoerper, SRXY1 antikoerper, TDF antikoerper, TDY antikoerper, SRYGENE antikoerper, Sry1 antikoerper, Sry3BI antikoerper, Tdf antikoerper, Tdy antikoerper, SRY antikoerper, sex determining region Y antikoerper, sex determining region of Chr Y antikoerper, SRY antikoerper, Sry antikoerper

Hintergrund:

Description: Transcriptional regulator that controls a genetic switch in male development. It is necessary and sufficient for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells (By similarity). In male adult brain involved in the maintenance of motor functions of dopaminergic neurons (By similarity). Involved in different aspects of gene regulation including promoter activation or repression (By similarity). Promotes DNA bending. SRY HMG box recognizes DNA by partial intercalation in the minor groove. Also involved in pre-mRNA splicing. Binds to the DNA consensus sequence 5'-[AT]AACAA[AT]-3'.

Gene: SRY

Molekulargewicht: 37 kDa

Gen-ID: 6736

UniProt: Q05066