ZFYVE19 Antikörper (Internal Region)

Produktnummer ABIN6257582

Produktdetails anti-ZFYVE19 Antikörper

Target: ZFYVE19 (Zinc Finger, FYVE Domain Containing 19 (ZFYVE19))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ZFYVE19 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: ZFYVE19 Antibody detects endogenous levels of total ZFYVE19.

Homologie: Horse,Rabbit,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human ZFYVE19, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu ZFYVE19

Target: ZFYVE19 (Zinc Finger, FYVE Domain Containing 19 (ZFYVE19))

Andere Bezeichnung: ZFYVE19 (ZFYVE19 Produkte)

Synonyme: ZFYVE19 antikoerper, mpfyve antikoerper, DKFZp469E1112 antikoerper, MPFYVE antikoerper, 1500041L05Rik antikoerper, zinc finger FYVE-type containing 19 antikoerper, zinc finger FYVE domain containing 19 antikoerper, zinc finger, FYVE domain containing 19 antikoerper, ZFYVE19 antikoerper, Zfyve19 antikoerper, zfyve19 antikoerper

Hintergrund:

Description: Key regulator of abscission step in cytokinesis: part of the cytokinesis checkpoint, a process required to delay abscission to prevent both premature resolution of intercellular chromosome bridges and accumulation of DNA damage. Together with CHMP4C, required to retain abscission-competent VPS4 (VPS4A and/or VPS4B) at the midbody ring until abscission checkpoint signaling is terminated at late cytokinesis. Deactivation of AURKB results in dephosphorylation of CHMP4C followed by its dissociation from ZFYVE19/ANCHR and VPS4 and subsequent abscission.

Gene: ZFYVE19

Molekulargewicht: 50 kDa

Gen-ID: 84936

UniProt: Q96K21