KSR2 Antikörper (Internal Region)
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- Target Alle KSR2 Antikörper anzeigen
- KSR2 (Kinase Suppressor of Ras 2 (KSR2))
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Bindungsspezifität
- Internal Region
- Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser KSR2 Antikörper ist unkonjugiert
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Applikation
- ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Spezifität
- KSR2 Antibody detects endogenous levels of total KSR2.
- Homologie
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Chicken,Xenopus
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human KSR2, corresponding to a region within the internal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product KSR2 Primärantikörper
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anti-Kinase Suppressor of Ras 2 (KSR2) (AA 411-500) antibody
KSR2 Reaktivität: Human ELISA, WB, RNAi Wirt: Maus Monoclonal 1G4 unconjugated
anti-Kinase Suppressor of Ras 2 (KSR2) (AA 411-500) antibodyKSR2 Reaktivität: Human ELISA, WB, IF Wirt: Maus Monoclonal 6C9 unconjugated
anti-Kinase Suppressor of Ras 2 (KSR2) (AA 603-638), (C-Term) antibodyKSR2 Reaktivität: Human WB, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB09886 unconjugated
anti-Kinase Suppressor of Ras 2 (KSR2) antibodyKSR2 Reaktivität: Human ELISA, WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Kinase Suppressor of Ras 2 (KSR2) (AA 159-296) antibodyKSR2 Reaktivität: Human ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Kinase Suppressor of Ras 2 (KSR2) (AA 411-500) antibodyKSR2 Reaktivität: Human ELISA, WB Wirt: Maus Polyclonal unconjugated
anti-Kinase Suppressor of Ras 2 (KSR2) (C-Term) antibodyKSR2 Reaktivität: Human WB, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated
anti-Kinase Suppressor of Ras 2 (KSR2) (AA 1-829) antibodyKSR2 Reaktivität: Human WB Wirt: Maus Polyclonal unconjugated
anti-Kinase Suppressor of Ras 2 (KSR2) (AA 411-500) antibodyKSR2 Reaktivität: Human ELISA, WB Wirt: Maus Monoclonal 6F12 unconjugated
anti-Kinase Suppressor of Ras 2 (KSR2) (Ile694) antibodyKSR2 Reaktivität: Human, Maus WB, IHC, IF, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- KSR2 (Kinase Suppressor of Ras 2 (KSR2))
- Andere Bezeichnung
- KSR2 (KSR2 Produkte)
- Synonyme
- kinase suppressor of ras 2 antikoerper, KSR2 antikoerper, Ksr2 antikoerper
- Hintergrund
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Description: Location-regulated scaffold connecting MEK to RAF. Has very low protein kinase activity and can phosphorylate MAP2K1 at several Ser and Thr residues with very low efficiency (in vitro). Interaction with BRAF enhances KSR2-mediated phosphorylation of MAP2K1 (in vitro). Blocks MAP3K8 kinase activity and MAP3K8-mediated signaling. Acts as a negative regulator of MAP3K3-mediated activation of ERK, JNK and NF-kappa-B pathways, inhibiting MAP3K3-mediated interleukin-8 production.
Gene: KSR2
- Molekulargewicht
- 108 kDa
- Gen-ID
- 283455
- UniProt
- Q6VAB6
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