AKAP10 Antikörper (N-Term)
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- Target Alle AKAP10 Antikörper anzeigen
- AKAP10 (A Kinase (PRKA) Anchor Protein 10 (AKAP10))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Ratte, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser AKAP10 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Spezifität
- AKAP10 Antibody detects endogenous levels of total AKAP10.
- Homologie
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human AKAP10, corresponding to a region within N-terminal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product AKAP10 Primärantikörper
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- Applikationshinweise
- WB 1:500-1:1000, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- AKAP10 (A Kinase (PRKA) Anchor Protein 10 (AKAP10))
- Andere Bezeichnung
- AKAP10 (AKAP10 Produkte)
- Synonyme
- MGC84612 antikoerper, AKAP10 antikoerper, fc10g11 antikoerper, wu:fc10g11 antikoerper, si:dkey-197m14.4 antikoerper, AKAP-10 antikoerper, D-AKAP-2 antikoerper, D-AKAP2 antikoerper, PRKA10 antikoerper, 1500031L16Rik antikoerper, B130049N18Rik antikoerper, D-akap2 antikoerper, Akap10 antikoerper, A-kinase anchoring protein 10 antikoerper, A-kinase anchoring protein 10 L homeolog antikoerper, A kinase (PRKA) anchor protein 10 antikoerper, AKAP10 antikoerper, akap10.L antikoerper, akap10 antikoerper, Akap10 antikoerper
- Hintergrund
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Description: Differentially targeted protein that binds to type I and II regulatory subunits of protein kinase A and anchors them to the mitochondria or the plasma membrane. Although the physiological relevance between PKA and AKAPS with mitochondria is not fully understood, one idea is that BAD, a proapoptotic member, is phosphorylated and inactivated by mitochondria-anchored PKA. It cannot be excluded too that it may facilitate PKA as well as G protein signal transduction, by acting as an adapter for assembling multiprotein complexes. With its RGS domain, it could lead to the interaction to G-alpha proteins, providing a link between the signaling machinery and the downstream kinase (By similarity).
Gene: AKAP10
- Molekulargewicht
- 73 kDa
- Gen-ID
- 11216
- UniProt
- O43572
- Pathways
- Regulation of G-Protein Coupled Receptor Protein Signaling
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