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Apoptosis Inhibitor 5 Antikörper (C-Term)

API5 Reaktivität: Human, Maus WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6257683
  • Target Alle Apoptosis Inhibitor 5 (API5) Antikörper anzeigen
    Apoptosis Inhibitor 5 (API5)
    Bindungsspezifität
    • 16
    • 15
    • 8
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 44
    • 27
    • 8
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 58
    • 2
    Kaninchen
    Klonalität
    • 58
    • 2
    Polyklonal
    Konjugat
    • 21
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Apoptosis Inhibitor 5 Antikörper ist unkonjugiert
    Applikation
    • 45
    • 23
    • 14
    • 11
    • 10
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Spezifität
    API-5 Antibody detects endogenous levels of total API-5.
    Homologie
    Pig,Horse,Sheep,Dog
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human API-5, corresponding to a region within C-terminal amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product API5 Primärantikörper
  • Applikationshinweise
    WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    Apoptosis Inhibitor 5 (API5)
    Andere Bezeichnung
    API5 (API5 Produkte)
    Synonyme
    AAC-11 antikoerper, AAC11 antikoerper, AI196452 antikoerper, api5l1 antikoerper, sr:nyz021 antikoerper, zgc:66211 antikoerper, wu:fb26c03 antikoerper, API-5B antikoerper, aac-11 antikoerper, aac11 antikoerper, api5 antikoerper, API-5A antikoerper, api5-A antikoerper, MGC83290 antikoerper, API5 antikoerper, apoptosis inhibitor 5 antikoerper, apoptosis inhibitor 5 S homeolog antikoerper, apoptosis inhibitor 5 L homeolog antikoerper, API5 antikoerper, Api5 antikoerper, api5 antikoerper, api5.S antikoerper, api5.L antikoerper
    Hintergrund

    Description: Antiapoptotic factor that may have a role in protein assembly. Negatively regulates ACIN1. By binding to ACIN1, it suppresses ACIN1 cleavage from CASP3 and ACIN1-mediated DNA fragmentation. Also known to efficiently suppress E2F1-induced apoptosis. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs.

    Gene: API5

    Molekulargewicht
    58 kDa
    Gen-ID
    8539
    UniProt
    Q9BZZ5
    Pathways
    Growth Factor Binding
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