TLK1 Antikörper (C-Term)

Produktnummer ABIN6257779

Produktdetails anti-TLK1 Antikörper

Target: TLK1 (Tousled-Like Kinase 1 (TLK1))

Bindungsspezifität: C-Term

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TLK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Spezifität: TLK1 Antibody detects endogenous levels of total TLK1.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human TLK1, corresponding to a region within C-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu TLK1

Target: TLK1 (Tousled-Like Kinase 1 (TLK1))

Andere Bezeichnung: TLK1 (TLK1 Produkte)

Synonyme: PKU-beta antikoerper, 4930545J15Rik antikoerper, fe11e12 antikoerper, si:dkey-251e16.4 antikoerper, tlk1 antikoerper, wu:fe11e12 antikoerper, TLK1 antikoerper, fb76h12 antikoerper, si:dkey-88m1.1 antikoerper, wu:fb76h12 antikoerper, DKFZp459L163 antikoerper, tousled like kinase 1 antikoerper, tousled-like kinase 1 antikoerper, tousled-like kinase 1b antikoerper, tousled like kinase 1 like antikoerper, serine/threonine-protein kinase TOUSLED antikoerper, tousled-like kinase 1a antikoerper, Serine/threonine-protein kinase tousled-like 1 antikoerper, TLK1 antikoerper, Tlk1 antikoerper, tlk1b antikoerper, TLK1L antikoerper, LOC542181 antikoerper, tlk1a antikoerper, tlk1 antikoerper, tlk-1 antikoerper

Hintergrund:

Description: Rapidly and transiently inhibited by phosphorylation following the generation of DNA double-stranded breaks during S-phase. This is cell cycle checkpoint and ATM-pathway dependent and appears to regulate processes involved in chromatin assembly. Isoform 3 phosphorylates and enhances the stability of the t-SNARE SNAP23, augmenting its assembly with syntaxin. Isoform 3 protects the cells from the ionizing radiation by facilitating the repair of DSBs. In vitro, phosphorylates histone H3 at 'Ser-10'.

Gene: TLK1

Molekulargewicht: 87 kDa

Gen-ID: 9874

UniProt: Q9UKI8