USP1 Antikörper (C-Term)
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- Target Alle USP1 Antikörper anzeigen
- USP1 (Ubiquitin Specific Peptidase 1 (USP1))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser USP1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Spezifität
- USP1 Antibody detects endogenous levels of total USP1.
- Homologie
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human USP1, corresponding to a region within C-terminal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product USP1 Primärantikörper
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- Applikationshinweise
- WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Haltbarkeit
- 12 months
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- Target
- USP1 (Ubiquitin Specific Peptidase 1 (USP1))
- Andere Bezeichnung
- USP1 (USP1 Produkte)
- Synonyme
- usp1-a antikoerper, UBP antikoerper, ubiquitin specific peptidase 1 antikoerper, ubiquitin specific peptidase 1 S homeolog antikoerper, USP1 antikoerper, usp1.S antikoerper, Usp1 antikoerper
- Hintergrund
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Description: Negative regulator of DNA damage repair which specifically deubiquitinates monoubiquitinated FANCD2 (PubMed:15694335). Also involved in PCNA-mediated translesion synthesis (TLS) by deubiquitinating monoubiquitinated PCNA (PubMed:16531995). Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity (PubMed:18082604, PubMed:26388029).
Gene: USP1
- Molekulargewicht
- 88 kDa
- Gen-ID
- 7398
- UniProt
- O94782
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