ERI1 Antikörper (C-Term)

Produktnummer ABIN6257805

Produktdetails anti-ERI1 Antikörper

Target: ERI1 (Exoribonuclease 1 (ERI1))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ERI1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: ERI1 Antibody detects endogenous levels of total ERI1.

Homologie: Pig,Zebrafish,Horse,Sheep,Rabbit,Dog,Chicken

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human ERI1, corresponding to a region within C-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu ERI1

Target: ERI1 (Exoribonuclease 1 (ERI1))

Andere Bezeichnung: ERI1 (ERI1 Produkte)

Synonyme: THEX1 antikoerper, thex1 antikoerper, zgc:110635 antikoerper, hexo antikoerper, Eri-1 antikoerper, 3'HEXO antikoerper, HEXO antikoerper, 3'hexo antikoerper, 3110010F15Rik antikoerper, Thex1 antikoerper, eri-1 antikoerper, RGD1308378 antikoerper, exoribonuclease 1 antikoerper, three prime repair exonuclease 1 antikoerper, exoribonuclease 1 L homeolog antikoerper, 3'-5' exonuclease eri-1 antikoerper, ERI1 antikoerper, CpipJ_CPIJ003945 antikoerper, eri1 antikoerper, eri1.L antikoerper, Eri1 antikoerper, eri-1 antikoerper

Hintergrund:

Description: RNA exonuclease that binds to the 3'-end of histone mRNAs and degrades them, suggesting that it plays an essential role in histone mRNA decay after replication. A 2' and 3'-hydroxyl groups at the last nucleotide of the histone 3'-end is required for efficient degradation of RNA substrates. Also able to degrade the 3'-overhangs of short interfering RNAs (siRNAs) in vitro, suggesting a possible role as regulator of RNA interference (RNAi). Requires for binding the 5'-ACCCA-3' sequence present in stem-loop structure. Able to bind other mRNAs. Required for 5.8S rRNA 3'-end processing. Also binds to 5.8s ribosomal RNA. Binds with high affinity to the stem-loop structure of replication-dependent histone pre-mRNAs.

Gene: ERI1

Molekulargewicht: 40 kDa

Gen-ID: 90459

UniProt: Q8IV48