Exonuclease 1 Antikörper (N-Term)
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- Target Alle Exonuclease 1 (EXO1) Antikörper anzeigen
- Exonuclease 1 (EXO1)
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Exonuclease 1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Spezifität
- EXO1 Antibody detects endogenous levels of total EXO1.
- Homologie
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human EXO1, corresponding to a region within N-terminal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product EXO1 Primärantikörper
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- Applikationshinweise
- WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- Exonuclease 1 (EXO1)
- Andere Bezeichnung
- EXO1 (EXO1 Produkte)
- Synonyme
- HEX1 antikoerper, hExoI antikoerper, 5730442G03Rik antikoerper, Msa antikoerper, EXO1 antikoerper, exoi antikoerper, fc16e04 antikoerper, wu:fc16e04 antikoerper, zgc:55521 antikoerper, exonuclease 1 antikoerper, hypothetical protein antikoerper, exonuclease I Exo1 antikoerper, RNA exonuclease antikoerper, exonuclease 1 S homeolog antikoerper, EXO1 antikoerper, Y17G7B.12 antikoerper, SJAG_01832 antikoerper, PAS_chr1-1_0377 antikoerper, Exo1 antikoerper, exo1 antikoerper, exo1.S antikoerper, LOC100338764 antikoerper
- Hintergrund
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Description: 5'->3' double-stranded DNA exonuclease which may also possess a cryptic 3'->5' double-stranded DNA exonuclease activity. Functions in DNA mismatch repair (MMR) to excise mismatch-containing DNA tracts directed by strand breaks located either 5' or 3' to the mismatch. Also exhibits endonuclease activity against 5'-overhanging flap structures similar to those generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Required for somatic hypermutation (SHM) and class switch recombination (CSR) of immunoglobulin genes. Essential for male and female meiosis.
Gene: EXO1
- Molekulargewicht
- 94 kDa
- Gen-ID
- 9156
- UniProt
- Q9UQ84
- Pathways
- DNA Reparatur, Production of Molecular Mediator of Immune Response
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