ARFGAP1 Antikörper (Internal Region)

Produktnummer ABIN6257929

Produktdetails anti-ARFGAP1 Antikörper

Target: ARFGAP1 (ADP-Ribosylation Factor GTPase Activating Protein 1 (ARFGAP1))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARFGAP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: ARFGAP1 Antibody detects endogenous levels of total ARFGAP1.

Homologie: Rabbit

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human ARFGAP1, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu ARFGAP1

Target: ARFGAP1 (ADP-Ribosylation Factor GTPase Activating Protein 1 (ARFGAP1))

Andere Bezeichnung: ARFGAP1 (ARFGAP1 Produkte)

Synonyme: ARF1GAP antikoerper, HRIHFB2281 antikoerper, AI115377 antikoerper, Arf1gap antikoerper, Arf GAP1 antikoerper, arf1gap antikoerper, atfb1 antikoerper, atfb3 antikoerper, jlns1 antikoerper, k(v)7.1 antikoerper, kcna8 antikoerper, kcna9 antikoerper, kv1.9 antikoerper, kv7.1 antikoerper, kvlqt1 antikoerper, lqt antikoerper, lqt1 antikoerper, rws antikoerper, sqt2 antikoerper, wrs antikoerper, ARFGAP3 antikoerper, ADP ribosylation factor GTPase activating protein 1 antikoerper, ADP-ribosylation factor GTPase activating protein 1 antikoerper, ADP ribosylation factor GTPase activating protein 1 S homeolog antikoerper, putative ADP-ribosylation factor GTPase activating protein 1 antikoerper, ATP-dependent RNA helicase DBP9 antikoerper, ARFGAP1 antikoerper, Arfgap1 antikoerper, arfgap1.S antikoerper, Tb11.01.6060 antikoerper, arfgap1 antikoerper, LMJF_32_1230 antikoerper, MGYG_02419 antikoerper

Hintergrund:

Description: GTPase-activating protein (GAP) for the ADP ribosylation factor 1 (ARF1). Involved in membrane trafficking and /or vesicle transport. Promotes hydrolysis of the ARF1-bound GTP and thus, is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles, a prerequisite for vesicle's fusion with target compartment. Probably regulates ARF1-mediated transport via its interaction with the KDELR proteins and TMED2. Overexpression induces the redistribution of the entire Golgi complex to the endoplasmic reticulum, as when ARF1 is deactivated. Its activity is stimulated by phosphoinosides and inhibited by phosphatidylcholine (By similarity).

Gene: ARFGAP1

Molekulargewicht: 60/48 kDa

Gen-ID: 55738

UniProt: Q8N6T3

Pathways: p53 Signalweg, ER-Nucleus Signaling, Unfolded Protein Response