BCOR Antikörper (Internal Region)

Produktnummer ABIN6257962

Produktdetails anti-BCOR Antikörper

Target: BCOR (BCL6 Co-Repressor (BCOR))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BCOR Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: BCOR Antibody detects endogenous levels of total BCOR.

Homologie: Pig,Bovine,Sheep,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human BCOR, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu BCOR

Target: BCOR (BCL6 Co-Repressor (BCOR))

Andere Bezeichnung: BCOR (BCOR Produkte)

Synonyme: ANOP2 antikoerper, MAA2 antikoerper, MCOPS2 antikoerper, BCOR antikoerper, RGD1562735 antikoerper, 5830466J11Rik antikoerper, 8430401K06Rik antikoerper, BcorR antikoerper, D930024N20Rik antikoerper, mKIAA1575 antikoerper, BCL6 corepressor antikoerper, BCL6 co-repressor antikoerper, BCL6 interacting corepressor antikoerper, BCOR antikoerper, bcor antikoerper, Bcor antikoerper

Hintergrund:

Description: Transcriptional corepressor. May specifically inhibit gene expression when recruited to promoter regions by sequence-specific DNA-binding proteins such as BCL6 and MLLT3. This repression may be mediated at least in part by histone deacetylase activities which can associate with this corepressor. Involved in the repression of TFAP2A, impairs binding of BCL6 and KDM2B to TFAP2A promoter regions. Via repression of TFAP2A acts as a negative regulator of osteo-dentiogenic capacity in adult stem cells, the function implies inhibition of methylation on histone H3 'Lys-4' (H3K4me3) and 'Lys-36' (H3K36me2).

Gene: BCOR

Molekulargewicht: 192 kDa

Gen-ID: 54880

UniProt: Q6W2J9