LGR6 Antikörper (Internal Region)

Produktnummer ABIN6258202

Produktdetails anti-LGR6 Antikörper

Target: LGR6 (Leucine-Rich Repeat-Containing G Protein-Coupled Receptor 6 (LGR6))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LGR6 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: LGR6 Antibody detects endogenous levels of total LGR6.

Homologie: Rabbit

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human LGR6, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu LGR6

Target: LGR6 (Leucine-Rich Repeat-Containing G Protein-Coupled Receptor 6 (LGR6))

Andere Bezeichnung: LGR6 (LGR6 Produkte)

Synonyme: LGR6 antikoerper, GPCR antikoerper, VTS20631 antikoerper, A530037C04Rik antikoerper, D830026M09 antikoerper, RGD1560339 antikoerper, leucine rich repeat containing G protein-coupled receptor 6 antikoerper, leucine-rich repeat-containing G protein-coupled receptor 6 antikoerper, LGR6 antikoerper, Lgr6 antikoerper

Hintergrund:

Description: Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a marker of multipotent stem cells in the epidermis. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. May act as a tumor suppressor.

Gene: LGR6

Molekulargewicht: 104 kDa

Gen-ID: 59352

UniProt: Q9HBX8