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GPR56 Antikörper

GPR56 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6258204
  • Target Alle GPR56 Antikörper anzeigen
    GPR56 (G Protein-Coupled Receptor 56 (GPR56))
    Reaktivität
    • 42
    • 22
    • 5
    • 4
    • 2
    Human
    Wirt
    • 35
    • 7
    Kaninchen
    Klonalität
    • 38
    • 4
    Polyklonal
    Konjugat
    • 22
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser GPR56 Antikörper ist unkonjugiert
    Applikation
    • 32
    • 21
    • 13
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Spezifität
    GPR56 antibody detects endogenous levels of total GPR56
    Kreuzreaktivität
    Human
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide
    Isotyp
    IgG
    Top Product
    Discover our top product GPR56 Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000 IHC 1:50-1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Target
    GPR56 (G Protein-Coupled Receptor 56 (GPR56))
    Andere Bezeichnung
    GPR56 (GPR56 Produkte)
    Synonyme
    fc49b10 antikoerper, wu:fc49b10 antikoerper, BFPP antikoerper, TM7LN4 antikoerper, TM7XN1 antikoerper, Cyt28 antikoerper, GPR56 antikoerper, adhesion G protein-coupled receptor G1 antikoerper, G protein-coupled receptor 56 antikoerper, ADGRG1 antikoerper, adgrg1 antikoerper, Adgrg1 antikoerper, GPR56 antikoerper
    Hintergrund

    Description: Receptor involved in cell adhesion and probably in cell-cell interactions. Mediates cell matrix adhesion in developing neurons and hematopoietic stem cells. Receptor for collagen III/COL3A1 in the developing brain and involved in regulation of cortical development, specifically in maintenance of the pial basement membrane integrity and in cortical lamination (By similarity). Binding to the COL3A1 ligand inhibits neuronal migration and activates the RhoA pathway by coupling to GNA13 and possibly GNA12 (PubMed:22238662). Plays a role in the maintenance of hematopoietic stem cells and/or leukemia stem cells in bone marrow niche (By similarity). Plays a critical role in cancer progression by inhibiting VEGFA production threreby inhibiting angiogenesis through a signaling pathway mediated by PRKCA (PubMed:16757564, PubMed:21724588). Plays an essential role in testis development (By similarity).

    Gene: ADGRG1

    Molekulargewicht
    78 kDa
    Gen-ID
    9289
    UniProt
    Q9Y653
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