GPR56 Antikörper
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- Target Alle GPR56 Antikörper anzeigen
- GPR56 (G Protein-Coupled Receptor 56 (GPR56))
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser GPR56 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Spezifität
- GPR56 antibody detects endogenous levels of total GPR56
- Kreuzreaktivität
- Human
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide
- Isotyp
- IgG
- Top Product
- Discover our top product GPR56 Primärantikörper
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- Applikationshinweise
- WB 1:500-1:2000 IHC 1:50-1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- Target
- GPR56 (G Protein-Coupled Receptor 56 (GPR56))
- Andere Bezeichnung
- GPR56 (GPR56 Produkte)
- Synonyme
- fc49b10 antikoerper, wu:fc49b10 antikoerper, BFPP antikoerper, TM7LN4 antikoerper, TM7XN1 antikoerper, Cyt28 antikoerper, GPR56 antikoerper, adhesion G protein-coupled receptor G1 antikoerper, G protein-coupled receptor 56 antikoerper, ADGRG1 antikoerper, adgrg1 antikoerper, Adgrg1 antikoerper, GPR56 antikoerper
- Hintergrund
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Description: Receptor involved in cell adhesion and probably in cell-cell interactions. Mediates cell matrix adhesion in developing neurons and hematopoietic stem cells. Receptor for collagen III/COL3A1 in the developing brain and involved in regulation of cortical development, specifically in maintenance of the pial basement membrane integrity and in cortical lamination (By similarity). Binding to the COL3A1 ligand inhibits neuronal migration and activates the RhoA pathway by coupling to GNA13 and possibly GNA12 (PubMed:22238662). Plays a role in the maintenance of hematopoietic stem cells and/or leukemia stem cells in bone marrow niche (By similarity). Plays a critical role in cancer progression by inhibiting VEGFA production threreby inhibiting angiogenesis through a signaling pathway mediated by PRKCA (PubMed:16757564, PubMed:21724588). Plays an essential role in testis development (By similarity).
Gene: ADGRG1
- Molekulargewicht
- 78 kDa
- Gen-ID
- 9289
- UniProt
- Q9Y653
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