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GAB2 Antikörper (C-Term)

GAB2 Reaktivität: Human, Maus, Ratte WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6258217
  • Target Alle GAB2 Antikörper anzeigen
    GAB2 (GRB2-Associated Binding Protein 2 (GAB2))
    Bindungsspezifität
    • 24
    • 21
    • 16
    • 11
    • 10
    • 7
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 122
    • 90
    • 84
    • 3
    • 3
    • 3
    • 3
    Human, Maus, Ratte
    Wirt
    • 121
    • 1
    • 1
    Kaninchen
    Klonalität
    • 123
    Polyklonal
    Konjugat
    • 39
    • 8
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Dieser GAB2 Antikörper ist unkonjugiert
    Applikation
    • 85
    • 39
    • 39
    • 39
    • 19
    • 15
    • 13
    • 9
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Spezifität
    Gab2 Antibody detects endogenous levels of total Gab2.
    Homologie
    Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human Gab2, corresponding to a region within C-terminal amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product GAB2 Primärantikörper
  • Applikationshinweise
    WB 1:500-1:1000, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    GAB2 (GRB2-Associated Binding Protein 2 (GAB2))
    Andere Bezeichnung
    GAB2 (GAB2 Produkte)
    Synonyme
    GAB2 antikoerper, AI463667 antikoerper, D130058I17Rik antikoerper, p97 antikoerper, GRB2 associated binding protein 2 antikoerper, GRB2-associated binding protein 2 antikoerper, growth factor receptor bound protein 2-associated protein 2 antikoerper, GAB2 antikoerper, gab2 antikoerper, Gab2 antikoerper
    Hintergrund

    Description: Adapter protein which acts downstream of several membrane receptors including cytokine, antigen, hormone, cell matrix and growth factor receptors to regulate multiple signaling pathways. Regulates osteoclast differentiation mediating the TNFRSF11A/RANK signaling. In allergic response, it plays a role in mast cells activation and degranulation through PI-3-kinase regulation. Also involved in the regulation of cell proliferation and hematopoiesis.

    Gene: GAB2

    Molekulargewicht
    74 kDa
    Gen-ID
    9846
    UniProt
    Q9UQC2
    Pathways
    T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, BCR Signaling, Warburg Effekt
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